ArticleAmerican journal of physiology. Endocrinology and metabolism2021
Skeletal muscle mitochondrial adaptations induced by long-term cigarette smoke exposure.
Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Mitochondrial Mechanisms of Resistance Exercise in COPD-Related Skeletal Muscle Dysfunction: A Narrative Review.International journal of chronic obstructive pulmonary disease · 2026Review
- Associations of serum cotinine and dietary inflammatory and antioxidant profiles with appendicular skeletal muscle mass in US adults: A cross-sectional study of data from NHANES 2011-2018.Tobacco induced diseases · 2026Article
- Muscle oxygenation levels in smokers and non-smokers during exercise: insights from a university-based study.European journal of applied physiology · 2025Article
- Marine-Derived Bioactive Compounds: A Promising Strategy for Ameliorating Skeletal Muscle Dysfunction in COPD.Marine drugs · 2025Review
- Mitochondrial free radicals contribute to cigarette smoke condensate-induced impairment of oxidative phosphorylation in the skeletal muscle in situ.Free radical biology & medicine · 2024Article
- Chronic aryl hydrocarbon receptor activity impairs muscle mitochondrial function with tobacco smoking.Journal of cachexia, sarcopenia and muscle · 2024Article
- Predicted lean body mass trajectories, and cancer risk and cancer-specific and all-cause mortality: A prospective cohort study.Journal of cachexia, sarcopenia and muscle · 2023Article
- Tissue-specific mitochondrial toxicity of cigarette smoke concentrate: consequence to oxidative phosphorylation.American journal of physiology. Heart and circulatory physiology · 2023Article
- Intraoperative Hemi-Diaphragm Electrical Stimulation Demonstrates Attenuated Mitochondrial Function without Change in Oxidative Stress in Cardiothoracic Surgery Patients.Antioxidants (Basel, Switzerland) · 2023Article
- Skeletal Muscle Mitochondrial Dysfunction in Chronic Obstructive Pulmonary Disease: Underlying Mechanisms and Physical Therapy Perspectives.Aging and disease · 2023Article
- Cigarette smoking and mitochondrial dysfunction in peripheral artery disease.Vascular medicine (London, England) · 2023Article
- Effects of Cigarette Smoke on Adipose and Skeletal Muscle Tissue: In Vivo and In Vitro Studies.Cells · 2022Article
- Article
- Cellular and Molecular Signatures of Oxidative Stress in Bronchial Epithelial Cell Models Injured by Cigarette Smoke Extract.International journal of molecular sciences · 2022Review
- Integrating Mechanisms of Exacerbated Atrophy and Other Adverse Skeletal Muscle Impact in COPD.Frontiers in physiology · 2022Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Because patients with chronic obstructive pulmonary disease (COPD) are often physically inactive, it is still unclear whether the lower respiratory capacity in the locomotor muscles of these patients is due to cigarette smoking per se or is secondary to physical deconditioning. Accordingly, the purpose of this study was to examine mitochondrial alterations in the quadriceps muscle of 10 mice exposed to 8 mo of cigarette smoke, a sedentary mouse model of emphysema, and 9 control mice, using immunoblotting, spectrophotometry, and high-resolution respirometry in permeabilized muscle fibers. Mice exposed to smoke displayed a twofold increase in the oxidative stress marker, 4-HNE, (
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