Evidence map›Paper›PMID 34121443›Full record

SynthesisJournal of managed care & specialty pharmacy2021

Comparative efficacy of lemborexant and other insomnia treatments: a network meta-analysis.

Heather McElroy, Beth O'Leary, Michael Adena, Renee Campbell, Amir Abbas Tahami Monfared, Genevieve Meier

Open access · greenAbstract readComparative StudyNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of managed care & specialty pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Comparative efficacy and safety of lemborexant 5 mg versus 10 mg for the treatment of insomnia: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Successful Methods for Switching from a Benzodiazepine Receptor Agonist to a Dual Orexin Receptor Antagonist for the Treatment of Insomnias.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Article
  6. Article
  7. Article
  8. Emerging and upcoming therapies in insomnia.Translational and clinical pharmacology · 2024
    Article
  9. Orexin antagonists for insomnia.Canadian family physician Medecin de famille canadien · 2024
    Article
  10. Article
  11. Switching to lemborexant for the management of insomnia in mental disorders: the SLIM study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  12. Article
  13. Lemborexant for insomnia.Australian prescriber · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heather McElroyDatalytics, Kingston ACT, Australia.
Beth O'LearyDatalytics, Kingston ACT, Australia.
Michael AdenaDatalytics, Kingston ACT, Australia.
Renee CampbellEisai Inc., Woodcliff Lake, NJ.
Amir Abbas Tahami MonfaredEisai Inc., Woodcliff Lake, NJ.
Genevieve MeierEisai Inc., Woodcliff Lake, NJ.
Eisai (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Orexin Receptor AntagonistsPyridinesPyrimidinesSleep Initiation and Maintenance DisordersHumansRandomized Controlled Trials as TopicTreatment OutcomelemborexantOrexin Receptor AntagonistsPyridinesPyrimidines

Identifiers

PMID34121443
PMCPMC10394202
OpenAlexW3170483517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.