Evidence map›Paper›PMID 34121417›Full record

ArticleJournal of the American Heart Association2021

Effect of Underlying Cardiometabolic Diseases on the Association Between Sedentary Time and All-Cause Mortality in a Large Japanese Population: A Cohort Analysis Based on the J-MICC Study.

Teruhide Koyama, Etsuko Ozaki, Nagato Kuriyama, Satomi Tomida, Tamami Yoshida, Ritei Uehara, Keitaro Tanaka, Megumi Hara, Asahi Hishida, Rieko Okada and 19 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Teruhide KoyamaDepartment of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Etsuko OzakiDepartment of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Nagato KuriyamaDepartment of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Satomi TomidaDepartment of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Tamami YoshidaDepartment of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Ritei UeharaDepartment of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
Keitaro TanakaDepartment of Preventive Medicine Faculty of Medicine Saga University Saga Japan.
Megumi HaraDepartment of Preventive Medicine Faculty of Medicine Saga University Saga Japan.
Asahi HishidaDepartment of Preventive Medicine Nagoya University Graduate School of Medicine Aichi Japan.
Rieko OkadaDepartment of Preventive Medicine Nagoya University Graduate School of Medicine Aichi Japan.
Yoko KuboDepartment of Preventive Medicine Nagoya University Graduate School of Medicine Aichi Japan.
Isao OzeDivision of Cancer Epidemiology and Prevention Aichi Cancer Center Research Institute Aichi Japan.
Yuriko N KoyanagiDivision of Cancer Information and Control Aichi Cancer Center Research Institute Aichi Japan.
Haruo MikamiCancer Prevention Center Chiba Cancer Center Research Institute Chiba Japan.
Yohko NakamuraCancer Prevention Center Chiba Cancer Center Research Institute Chiba Japan.
Ippei ShimoshikiryoDepartment of International Island and Community Medicine Kagoshima University Graduate School of Medical and Dental Sciences Kagoshima Japan.
Toshiro TakezakiDepartment of International Island and Community Medicine Kagoshima University Graduate School of Medical and Dental Sciences Kagoshima Japan.
Sadao SuzukiDepartment of Public Health Nagoya City University Graduate School of Medical Sciences Aichi Japan.
Takahiro OtaniDepartment of Public Health Nagoya City University Graduate School of Medical Sciences Aichi Japan.
Kiyonori KurikiLaboratory of Public Health School of Food and Nutritional Sciences University of Shizuoka Japan.
Naoyuki TakashimaDepartment of Public Health Faculty of Medicine Kindai University Osaka Japan.
Aya KadotaDepartment of Public Health Shiga University of Medical Science Shiga Japan.
Kokichi ArisawaDepartment of Preventive Medicine Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
Sakurako Katsuura-KamanoDepartment of Preventive Medicine Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
Hiroaki IkezakiDepartment of General Internal Medicine Kyushu University Hospital Fukuoka Japan.
Masayuki MurataDepartment of General Internal Medicine Kyushu University Hospital Fukuoka Japan.
Kenji TakeuchiDepartment of Preventive Medicine Nagoya University Graduate School of Medicine Aichi Japan.
Kenji WakaiDepartment of Preventive Medicine Nagoya University Graduate School of Medicine Aichi Japan.
Japan Multi‐Institutional Collaborative Cohort (J‐MICC) Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background This study aimed to determine the association between sedentary time and mortality with regard to leisure-time physical activity with or without cardiometabolic diseases such as hypertension, dyslipidemia, and diabetes mellitus. Methods and Results Using data from the J-MICC (Japan Multi-Institutional Collaborative Cohort) Study, 64 456 participants (29 022 men, 35 434 women) were analyzed. Hazard ratios (HRs) and 95% CIs were used to characterize the relative risk of all-cause mortality to evaluate its association with sedentary time (categorical variables: <5, 5 to <7, 7 to <9, ≥9 h/d and 2-hour increments in exposure) according to the self-reported hypertension, dyslipidemia, and diabetes mellitus using a Cox proportional hazards model. A total of 2257 participants died during 7.7 years of follow-up. The corresponding HRs for each 2-hour increment in sedentary time among participants with all factors, no factors, hypertension, dyslipidemia, and diabetes mellitus were 1.153 (95% CI, 1.114-1.194), 1.125 (95% CI, 1.074-1.179), 1.202 (95% CI, 1.129-1.279), 1.176 (95% CI, 1.087-1.273), and 1.272 (95% CI, 1.159-1.396), respectively. Furthermore, when analyzed according to the combined different factors (hypertension, dyslipidemia, and diabetes mellitus), HRs increased with each additional factor, and participants reporting all 3 conditions had the highest HR of 1.417 (95% CI, 1.162-1.728) independently of leisure-time metabolic equivalents. Conclusions The association between sedentary time and increased mortality is stronger among patients with hypertension, dyslipidemia, and diabetes mellitus regardless of leisure-time physical activity in a large Japanese population.

Indexed as

MortalitySedentary BehaviorAdultAgedCardiovascular DiseasesCause of DeathCohort StudiesDiabetes MellitusDyslipidemiasFemaleHumansHypertensionJapanLeisure ActivitiesMaleMiddle Agedall‐cause mortalitydiabetes mellitusdyslipidemiahypertensionsedentary time

Identifiers

PMID34121417
PMCPMC8403304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.