Evidence map›Paper›PMID 34121359›Full record

ReviewPhysiological reports2021

SARS-CoV-2 and hypertension.

Briyanth Ravichandran, Daniela Grimm, Marcus Krüger, Sascha Kopp, Manfred Infanger, Markus Wehland

Open access · goldAbstract readReview
In one paragraph

Review in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Observational
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  7. Article
  8. Article
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  11. Article
  12. Comorbidities of COVID-19 Patients.Medicina (Kaunas, Lithuania) · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Briyanth RavichandranDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Daniela GrimmDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-4991-3105
Marcus KrügerDepartment of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.ORCID 0000-0003-1120-0246
Sascha KoppDepartment of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.ORCID 0000-0001-5829-6455
Manfred InfangerDepartment of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Markus WehlandDepartment of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.ORCID 0000-0002-8160-859X
Otto-von-Guericke-Universität Magdeburg · DEAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this review is to give an overview of the pathophysiological effects of the Coronavirus Disease 2019 (COVID-19) in relation to hypertension (HT), with a focus on the Renin-Angiotensin-Aldosterone System (RAAS) and the MAS receptor. HT is a multifactorial disease and a public health burden, as it is a risk factor for diseases like stroke, coronary artery disease, and heart failure, leading to 10.4 million deaths yearly. Blood pressure is regulated by the RAAS. The system consists of two counter-regulatory axes: ACE/ANG-II/AT

Indexed as

Angiotensin-Converting Enzyme InhibitorsCOVID-19HumansHypertensionPandemicsRenin-Angiotensin SystemRisk FactorsSARS-CoV-2Angiotensin-Converting Enzyme InhibitorsCOVID-19hypertensionMAS-receptorrenin-angiotensin-aldosterone systemSARS-CoV-2

Identifiers

PMID34121359
PMCPMC8198473
OpenAlexW3172909022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.