Evidence map›Paper›PMID 34121304›Full record

ArticleJournal of cosmetic dermatology2021

Virgin coconut oil as prophylactic therapy against alcohol damage on skin in COVID times.

Punit Saraogi, Vaibhav Kaushik, Ritesh Chogale, Sneha Chavan, Vaishali Gode, Sudhakar Mhaskar

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Punit SaraogiEverything Skin & Hair, Medical & Aesthetic Dermatology Clinic, Mumbai, India.
Vaibhav KaushikMarico R&D Center, Marico Limited, Mumbai, India.ORCID https://orcid.org/0000-0002-3959-3128
Ritesh ChogaleMarico R&D Center, Marico Limited, Mumbai, India.
Sneha ChavanMarico R&D Center, Marico Limited, Mumbai, India.
Vaishali GodeMarico R&D Center, Marico Limited, Mumbai, India.
Sudhakar MhaskarMarico R&D Center, Marico Limited, Mumbai, India.
Marico (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased frequency of using alcohol-based hand sanitizers (ABHS) by consumers during COVID times have resulted in increased incidences of skin issues on palms.

objective(1) To quantify skin damage with increased usage frequency of ABHS by consumers and (2) To evaluate Virgin Coconut Oil (VCO) as natural prophylactic agent to counter the adverse effects.

methodsIn-home usage study was carried out with 60 volunteers for a 15-day intervention-Control Group: 6 applications per day of ABHS and Test Group: Overnight VCO use (6-8 drops) followed by 6× usage per day of ABHS. This leg included dermatological evaluation and WHO Self-Assessment Scale for skin health. Another leg of measurement included non-invasive instrumental study (Moisture & TEWL Probes, Tape Strip for protein content and IR spectroscopy for protein & lipid content) on forearm of 12 subjects (25-60 years age) with and without VCO application and repeated alcohol exposure.

resultsIn-home usage study established consumer experiencing skin protective effect of VCO in the context of ABHS onslaught. 25% increase in perceived moisture content was recorded for VCO users, using WHO Self-Assessment Scale. Instrumental studies confirmed an increase in TEWL and decrease in lipids & protein content. Overnight VCO application resists the extraction which builds up with repeated application.

conclusionsCurrent work provides evidence of compromised hand skin barrier with ABHS daily usage. Overnight VCO application helps prepare the skin for next day alcohol use. Based on the findings, a regimen of overnight VCO application on hands as a natural prophylactic is recommended.

Indexed as

COVID-19Coconut OilEthanolHumansLipidsSARS-CoV-2Coconut OilEthanolLipidsalcohol-based hand sanitizersskin damageskin lipid extractionskin moisturizationvirgin coconut oil

Identifiers

PMID34121304
PMCPMC8447131
OpenAlexW3169600959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.