Evidence map›Paper›PMID 34121211›Full record

ArticleMagnetic resonance in chemistry : MRC2021

Hyperpolarization of common antifungal agents with SABRE.

Keilian MacCulloch, Patrick Tomhon, Austin Browning, Evan Akeroyd, Sören Lehmkuhl, Eduard Y Chekmenev, Thomas Theis

Abstract read
In one paragraph

Article in Magnetic resonance in chemistry : MRC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Benchtop NMR signal enhancement of metabolites in urine extract using SABRE.Chemical communications (Cambridge, England) · 2026
    Article
  4. EfficientJournal of magnetic resonance open · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Keilian MacCullochDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0002-4506-5057
Patrick TomhonDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0003-3202-9812
Austin BrowningDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0001-9190-1215
Evan AkeroydDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.
Sören LehmkuhlDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0002-1321-7677
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, MI, USA.ORCID 0000-0002-8745-8801
Thomas TheisDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0001-6779-9978

Funding

Molecular MRI of Brain Metabolism Enabled by Long-Lived Spin StatesR01EB029829 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THEIS, THOMAS · 2020 to 2020
$807k
Molecular imaging with a hyperpolarized Vitamin ShotR21EB025313 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THEIS, THOMAS · 2018 to 2019
$661k
Edward Mallinckrodt, Jr. FoundationNIBIB NIH HHS NIH R01EB029829NIBIB NIH HHS NIH R21-EB025313NIBIB NIH HHS R01 EB029829NIBIB NIH HHS R21 EB025313North Carolina Biotechnology Center 2019-TRG-6707
6 · The paper itself

Abstract

Signal amplification by reversible exchange (SABRE) is a robust and inexpensive hyperpolarization (HP) technique to enhance nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) signals using parahydrogen (pH

Indexed as

Antifungal AgentsMagnetic Resonance ImagingCatalysisMagnetic Resonance SpectroscopyNitrogen IsotopesAntifungal AgentsNitrogen Isotopes15N1Hantifungalsclotrimazole and fluconazolecontrast agentshyperpolarizationNMRparahydrogenSABREvoriconazole

Identifiers

PMID34121211
PMCPMC8595556

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.