Evidence map›Paper›PMID 34121162›Full record

ReviewEnvironmental science and pollution research international2021

Exploring the therapeutic potential of omega-3 fatty acids in depression.

Priyanshi Sikka, Tapan Behl, Sanchay Sharma, Aayush Sehgal, Saurabh Bhatia, Ahmed Al-Harrasi, Sukhbir Singh, Neelam Sharma, Lotfi Aleya

Abstract readReview
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In one paragraph

Review in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Priyanshi Sikka *Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Tapan Behl *Chitkara College of Pharmacy, Chitkara University, Punjab, India. tapanbehl131@gmail.com.ORCID http://orcid.org/0000-0003-0993-7708
Sanchay SharmaChitkara College of Pharmacy, Chitkara University, Punjab, India.
Aayush SehgalChitkara College of Pharmacy, Chitkara University, Punjab, India.
Saurabh BhatiaAmity Institute of Pharmacy, Amity University, Gurugram, Haryana, India.
Ahmed Al-HarrasiNatural & Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, Nizwa, Oman.
Sukhbir SinghChitkara College of Pharmacy, Chitkara University, Punjab, India.
Neelam SharmaChitkara College of Pharmacy, Chitkara University, Punjab, India.
Lotfi AleyaChrono-Environment Laboratory, UMR CNRS 6249, Bourgogne Franche-Comté University, Besançon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omega-3 fatty acids have been acknowledged for their number of holdings on an individual's health. Not only in physical valuation but also in managing psychiatric disorders, omega-3 fatty acids have been found to be a powerful formula. It is proclaimed that depressive patients suffer anomaly with the levels of omega-3 polyunsaturated fatty acids in the body, coupled with insignificant EPA and DHA. Enhancement in brain functioning, neuronal functions, and paying attention in interacting with the brain cells are some of the additional tasks, being performed by the supplementation of omega-3 fatty acids. The leading and primary source via dietary supplementation involves the involvement of fish and fish products. These are hypothesized to be the best and dominant source for omega-3 fatty acids. Consumption of omega-3 fatty acid is well safe, that physician highly favors intake of these supplements, remarkably in the case of pregnant women. However, treating this serious life-threatening mental disorder leads to many adverse effects when treated with antidepressants. The dose range includes 1g/d to 10g/d, which is to be incorporated by the patient. It is also tested that the combination of EPA and DHA is found to be more efficacious for a person in treating and preventing depressive symptoms. Some studies verify the supplementation of omega-3 fatty acids in diet was coequally productive and successful with minimal side effects when analyzed with antidepressants. Despite these facts, much research is still needed and presently in process for long-term safety and studying the role of omega-3 fatty acids in human health.

Indexed as

DepressionFatty Acids, Omega-3AnimalsAntidepressive AgentsBrainDietary SupplementsFatty AcidsFemaleHumansPregnancyAntidepressive AgentsFatty AcidsFatty Acids, Omega-3AntidepressantsDocosahexaenoic acidEicosapentaenoic acidOmega-3 fatty acidsSupplementation

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.