Evidence map›Paper›PMID 34121127›Full record

ArticleJournal of rehabilitation medicine2021

Diagnosing sarcopenia: Functional perspectives and a new algorithm from the ISarcoPRM.

Murat Kara, Bayram Kaymak, Walter Frontera, Ayşe Merve Ata, Vincenzo Ricci, Timur Ekiz, Ke-Vin Chang, Der-Sheng Han, Xanthi Michail, Michael Quittan and 4 more

7 registry-linked trialsAbstract read
In one paragraph

Article in Journal of rehabilitation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 92 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04960007 unknown statusnot on this map

Comparison of the Swallowing Functions of the Sarcopenia and Dynapenia Patients

TypeobservationalSponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital OrganizationRan2021 to 2021Enrolled108ConditionsSarcopenia, Dysphagia, Swallowing Disorder
NCT06354348 nacompletednot on this mapstarted 2023, after this paper: background citation

Practical Ultrasonographic Detection of Sarcopenia in Patients With Long-term Gastrectomy: A Cross-sectional Case-control Study

TypeinterventionalSponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalRan2023 to 2024Enrolled90ConditionsSarcopenia, GastrectomyArmsUSG, Grip strength, Chair stand test (CST)
NCT06398704 completednot on this mapstarted 2024, after this paper: background citation

Investigation of the Effects of Sarcopenia and Dynapenia on Inspiratory Muscle Strength and Cardiorespiratory Fitness in Geriatric Individuals

TypeobservationalSponsorHacettepe UniversityRan2024 to 2024Enrolled75ConditionsGeriatric IndividualsArmsStandart of care
NCT06508957 completednot on this mapstarted 2023, after this paper: background citation

Assessment of Sarcopenia and Bone Mineral Density Relation in Hip Fracture Patients: A Cross-Sectional Study by Using STAR Value

Typeobservational_patient_registrySponsorKastamonu UniversityRan2023 to 2023Enrolled35ConditionsSarcopenia, Hip Fractures
NCT06889415 recruitingnot on this mapstarted 2023, after this paper: background citation

The Frequency of Osteosarcopenia in Patients With Rheumatoid Arthritis and the Factors Affecting the Sarcopenia-osteoporosis Relationship

Typeobservational_patient_registrySponsorKonya Beyhekim Training and Research HospitalRan2023 to 2025Enrolled200ConditionsOsteosarcopenia, Rheumatoid Arthritis (RA), SarcopeniaArmsOsteosarcopenia in Patients with Rheumatoid Arthritis, Osteosarcopenia in Healthy Control Group
NCT06958302 recruitingnot on this mapstarted 2025, after this paper: background citation

The Relation Between Diabetic Neuropathy and Muscle Mass in Type 2 Diabetes Mellitus Patients

TypeobservationalSponsorAin Shams UniversityRan2025 to 2026Enrolled60ConditionsDiabetic Neuropathy, Sarcopenia
NCT07014514 completednot on this mapstarted 2025, after this paper: background citation

Investigation of Sarcopenia Severity in Patients With Parkinson's Disease

TypeobservationalSponsorAnkara UniversityRan2025 to 2025Enrolled65ConditionsParkinson Disease
3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Frailty in COPD: Clinical Impact, Diagnosis, Biomarkers, and Management Strategies.International journal of chronic obstructive pulmonary disease · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Murat KaraPhysical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey. E-mail: mkaraftr@yahoo.com.
Bayram Kaymak
Walter Frontera
Ayşe Merve Ata
Vincenzo Ricci
Timur Ekiz
Ke-Vin Chang
Der-Sheng Han
Xanthi Michail
Michael Quittan
Jae-Young Lim
Jonathan F Bean
Franco Franchignoni
Levent Özçakar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia is an important public health problem, characterized by age-related loss of muscle mass and muscle function. It is a precursor of physical frailty, mobility limitation, and premature death. Muscle loss is mainly due to the loss of type II muscle fibres, and progressive loss of motor neurones is thought to be the primary underlying factor. Anterior thigh muscles undergo atrophy earlier, and the loss of anterior thigh muscle function may therefore be an antecedent finding. The aim of this review is to provide an in-depth (and holistic) neuromusculoskeletal approach to sarcopenia. In addition, under the umbrella of the International Society of Physical and Rehabilitation Medicine (ISPRM), a novel diagnostic algorithm is proposed, developed with the consensus of experts in the special interest group on sarcopenia (ISarcoPRM). The advantages of this algorithm over the others are: special caution concerning disorders related to the renin-angiotensin system at the case finding stage; emphasis on anterior thigh muscle mass and function loss; incorporation of ultrasound for the first time to measure the anterior thigh muscle; and addition of a chair stand test as a power/performance test to assess anterior thigh muscle function. Refining and testing the algorithm remains a priority for future research.

Indexed as

AgedAlgorithmsFemaleFrailtyHumansMaleSarcopeniafrailtyfunctionInternational Society of Physical and Rehabilitation MedicinemusclequadricepsSonographic Thigh Adjustment Ratioultrasound

Identifiers

PMID34121127
PMCPMC8814891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.