Evidence map›Paper›PMID 34121013›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Acquired Coagulation Factor V Inhibitor That Was Successfully Treated with Oral Corticosteroid Therapy.

Yoshihiro Yokota, Osamu Inatomi, Minami Nakagawa, Kazuki Kakuda, Kousuke Hiroe, Shigeki Sakai, Rie Osaki, Masaki Iwasa, Masahiro Kawahara, Katsuyuki Kito and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yoshihiro YokotaDepartment of Gastroenterology, Nagahama Red Cross Hospital, Japan.
Osamu InatomiDepartment of Medicine, Shiga University of Medical Science, Japan.
Minami NakagawaDepartment of Clinical Laboratory Medicine, Nagahama Red Cross Hospital, Japan.
Kazuki KakudaDepartment of Gastroenterology, Nagahama Red Cross Hospital, Japan.
Kousuke HiroeDepartment of Gastroenterology, Nagahama Red Cross Hospital, Japan.
Shigeki SakaiDepartment of Gastroenterology, Nagahama Red Cross Hospital, Japan.
Rie OsakiDepartment of Gastroenterology, Nagahama Red Cross Hospital, Japan.
Masaki IwasaDepartment of Medicine, Shiga University of Medical Science, Japan.
Masahiro KawaharaDepartment of Medicine, Shiga University of Medical Science, Japan.
Katsuyuki KitoDepartment of Medicine, Shiga University of Medical Science, Japan.
Akira AndohDepartment of Medicine, Shiga University of Medical Science, Japan.
Hiromichi BambaDepartment of Gastroenterology, Nagahama Red Cross Hospital, Japan.
Nagaoka Red Cross Hospital · JPShiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired coagulation factor V (FV) inhibitors are rare disorders in which antibodies against FV develop under various conditions. We herein report the case of a 71-year-old woman with FV inhibitor during radiochemotherapy for pancreatic cancer. Multiple purpuras suddenly appeared on her bilateral upper limbs with prolonged coagulation data (APTT 97.3 seconds). The FV activity was less than 3% and the FV inhibitor was positive (1.7 B.U./mL). Oral prednisolone induced a rapid normalization of the coagulation data and FV activity and a rapid disappearance of FV inhibitor within 7 days. Early diagnosis and treatment may therefore be important in cases of FV inhibitor.

Indexed as

Blood Coagulation Factor InhibitorsFactor VAdrenal Cortex HormonesAgedBlood CoagulationBlood Coagulation TestsFemaleHumansAdrenal Cortex HormonesBlood Coagulation Factor InhibitorsFactor Vcorticosteroidsfactor V inhibitorpancreatic cancer

Identifiers

PMID34121013
PMCPMC8429299
OpenAlexW3172354095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.