Evidence map›Paper›PMID 34121008›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Possible Neoangiogenesis in Achilles Tendon Xanthoma with Familial Hypercholesterolemia: A Novel Approach to Achilles Tendon Xanthoma.

Tetsu Tanaka, Kazuyuki Yahagi, Osamu Wada, Kai Ninomiya, Yu Horiuchi, Masahiko Asami, Hitomi Yuzawa, Kota Komiyama, Jun Tanaka, Jiro Aoki and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Tetsu TanakaDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Kazuyuki YahagiDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Osamu WadaDivision of Physiological Laboratory, Mitsui Memorial Hospital, Japan.
Kai NinomiyaDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Yu HoriuchiDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Masahiko AsamiDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Hitomi YuzawaDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Kota KomiyamaDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Jun TanakaDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Jiro AokiDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Akitake SuzukiDivision of Rheumatology, Mitsui Memorial Hospital, Japan.
Kazuho IshizakiDivision of Physiological Laboratory, Mitsui Memorial Hospital, Japan.
Kengo TanabeDivision of Cardiology, Mitsui Memorial Hospital, Japan.
Mitsui Memorial Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achilles tendon xanthoma (ATX) is one of the typical features of familial hypercholesterolemia (FH). The morphological evaluation of ATX by X-ray radiography is widely recognized; however, the utility of other imaging modalities remains unclear. We herein report two cases of FH in which Doppler ultrasound imaging demonstrated a microvascular flow in ATX that only rarely could be observed in normal Achilles tendons. Neoangiogenesis accompanies chronic inflammation and it may play an important role in the deposition of cholesterol crystals leading to ATX. In addition to the morphological evaluation of ATX, the assessment of neoangiogenesis may therefore be essential for the evaluation of ATX.

Indexed as

Achilles TendonHyperlipoproteinemia Type IIXanthomatosisHumansUltrasonographyX-Raysachilles tendon xanthomafamilial hypercholesterolemiamagnetic resonance imagingneoangiogenesissuperb micro-vascular imagingultrasonography

Identifiers

PMID34121008
PMCPMC8758461
OpenAlexW3168943685

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.