Evidence map›Paper›PMID 34121006›Full record

ArticleInternal medicine (Tokyo, Japan)2021

High-grade Primary Central Nervous System Lymphomatoid Granulomatosis: Successful Rituximab Monotherapy.

Sakiko Harada, Jun Ando, Miki Ando, Hideaki Nitta, Tadaaki Inano, Yusuke Hirasawa, Yoshiki Furukawa, Shintaro Kinoshita, Akihide Kondo, Koichi Ohshima and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sakiko HaradaDepartment of Hematology, Juntendo University School of Medicine, Japan.
Jun AndoDepartment of Hematology, Juntendo University School of Medicine, Japan.
Miki AndoDepartment of Hematology, Juntendo University School of Medicine, Japan.
Hideaki NittaDepartment of Hematology, Juntendo University School of Medicine, Japan.
Tadaaki InanoDepartment of Hematology, Juntendo University School of Medicine, Japan.
Yusuke HirasawaDepartment of Dermatology, Juntendo University School of Medicine, Japan.
Yoshiki FurukawaDepartment of Hematology, Juntendo University School of Medicine, Japan.
Shintaro KinoshitaDepartment of Hematology, Juntendo University School of Medicine, Japan.
Akihide KondoDepartment of Neurosurgery, Juntendo University School of Medicine, Japan.
Koichi OhshimaDepartment of Pathology, School of Medicine, Kurume University, Japan.
Norio KomatsuDepartment of Hematology, Juntendo University School of Medicine, Japan.
Juntendo University · JPKurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary central nervous system (CNS) presentation of lymphomatoid granulomatosis (LYG) is rare, and no standard therapy for LYG with primary CNS symptoms exists. CNS-LYG patients usually survive for only less than a year from diagnosis. This is the first report of high-grade primary CNS-LYG with monoclonality that was successfully treated with rituximab monotherapy, resulting in a durable remission for more than 1 year in a 66-year-old woman with pemphigus vulgaris who was also on immunosuppressive therapy.

Indexed as

Lymphomatoid GranulomatosisCentral Nervous SystemFemaleHumansRituximabRituximabcentral nervous systemhigh-grade lymphomatoid granulomatosispemphigus vulgarisrituximab

Identifiers

PMID34121006
PMCPMC8710380
OpenAlexW3169144360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.