ArticleAtherosclerosis2021
Abdominal aortic calcification is associated with a higher risk of injurious fall-related hospitalizations in older Australian women.
Article in Atherosclerosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Effect of osteoporosis medications on vascular and valvular calcification: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Pooled it
- Cardiovascular Disorders and Falls Among Older Adults: A Systematic Review and Meta-Analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Pooled it
- Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study.GeroScience · 2026Article
- Automated abdominal aortic calcification and trabecular bone score independently predict incident fracture during routine osteoporosis screening.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Association of muscle strength with abdominal aortic calcification.The Journal of international medical research · 2026Article
- Association between serum alpha Klotho levels and the likelihood of abdominal aortic calcification.Scientific reports · 2026Article
- Article
- A prospective cohort study on the joint associations of abdominal aortic calcification and systemic inflammation response index with mortality risk.Scientific reports · 2025Article
- Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population.Preventive medicine reports · 2025Article
- Deep learning-based automated quantification system for abdominal aortic calcification: multicenter cohort study for algorithm development and clinical validation.Frontiers in cardiovascular medicine · 2025Article
- Associations between type 2 diabetes mellitus and risk of falls among community-dwelling elderly people in Guangzhou, China: a prospective cohort study.BMC geriatrics · 2024Article
- Abdominal aortic calcification is an independent predictor of perioperative blood loss in posterior spinal fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Extent of Abdominal Aortic Calcification Is Associated With Incident Rapid Weight Loss Over 5 Years: The Perth Longitudinal Study of Ageing Women.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Machine-Learning Assessed Abdominal Aortic Calcification is Associated with Long-Term Fall and Fracture Risk in Community-Dwelling Older Australian Women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023Article
- Machine learning for abdominal aortic calcification assessment from bone density machine-derived lateral spine images.EBioMedicine · 2023Article
- Article
- Cardiovascular Safety of Antifracture Medications in Patients With Osteoporosis: A Narrative Review of Evidence From Randomized Studies.JBMR plus · 2021Review
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 4 countries.
Funding
Abstract
BACKGROUNDS AND
aimsAbdominal aortic calcification (AAC) is associated with weaker grip strength, an established risk factor for fall-related hospitalizations. However, its association with long-term fall-related hospitalisations remains unknown. This study investigated the association between AAC and long-term fall-related hospitalizations in community-dwelling older women.
methodsFall-related hospitalizations were obtained from linked data over 14.5-years in a prospective cohort of 1053 older women (mean age 75.0 ± 2.6 years). At baseline (1998/99), AAC was assessed from lateral spine images obtained using dual-energy X-ray absorptiometry, and scored using a semi-quantitative method (AAC24, range 0-24). The presence of any AAC was defined by AAC24 ≥ 1.
resultsOver 14.5-years, 413 (39.2%) women experienced a fall-related hospitalization. In the multivariable-adjusted model, each unit increase in baseline AAC24 was associated with a 3% increase in relative hazards for a fall-related hospitalization (HR 1.03 95%CI, 1.01 to 1.07). Compared to women with no AAC, women with any AAC had a 40% (HR 1.40 95%CI, 1.11 to 1.76) and 39% (HR 1.39 95%CI, 1.10 to 1.76) greater risk for fall-related hospitalizations in the minimal and multivariable-adjusted models, respectively. This relationship was not attenuated by including measures of muscle function such as grip strength and timed-up-and-go.
conclusionsThe presence of AAC is associated with long-term fall-related hospitalizations risk, independent of muscle function, in community-dwelling older women. Concurrent assessment of AAC may be a simple and cost-effective way to identify older women at higher risk of falling as part of routine osteoporosis screening.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.