Evidence map›Paper›PMID 34120663›Full record

ArticleParasitology2021

Absence of

M A Knox, J C Garcia-R, P Ogbuigwe, A Pita, N Velathanthiri, D T S Hayman

Abstract read
In one paragraph

Article in Parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Monitoring of cryptosporidiosis: a shift in circulatingEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  2. Article
  3. A review of recentCurrent research in parasitology & vector-borne diseases · 2025
    Review
  4. Microphysiological gut-on-chip enables extendedFrontiers in cellular and infection microbiology · 2025
    Article
  5. Article
  6. Marked increase in cryptosporidiosis cases, Spain, 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Molecular Detection ofVeterinary sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M A KnoxMassey University, School of Veterinary Science, Palmerston North, Manawatu-Wanganui, New Zealand.ORCID 0000-0001-6764-6568
J C Garcia-RMassey University, School of Veterinary Science, Palmerston North, Manawatu-Wanganui, New Zealand.ORCID 0000-0002-6665-9671
P OgbuigweMassey University, School of Veterinary Science, Palmerston North, Manawatu-Wanganui, New Zealand.
A PitaMassey University, School of Veterinary Science, Palmerston North, Manawatu-Wanganui, New Zealand.
N VelathanthiriMassey University, School of Veterinary Science, Palmerston North, Manawatu-Wanganui, New Zealand.
D T S HaymanMassey University, School of Veterinary Science, Palmerston North, Manawatu-Wanganui, New Zealand.ORCID 0000-0003-0087-3015

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease-2019 (Covid-19) nonpharmaceutical interventions have proven effective control measures for a range of respiratory illnesses throughout the world. These measures, which include isolation, stringent border controls, physical distancing and improved hygiene also have effects on other human pathogens, including parasitic enteric diseases such as cryptosporidiosis. Cryptosporidium infections in humans are almost entirely caused by two species: C. hominis, which is primarily transmitted from human to human, and Cryptosporidium parvum, which is mainly zoonotic. By monitoring Cryptosporidium species and subtype families in human cases of cryptosporidiosis before and after the introduction of Covid-19 control measures in New Zealand, we found C. hominis was completely absent after the first months of 2020 and has remained so until the beginning of 2021. Nevertheless, C. parvum has followed its typical transmission pattern and continues to be widely reported. We conclude that ~7 weeks of isolation during level 3 and 4 lockdown period interrupted the human to human transmission of C. hominis leaving only the primarily zoonotic transmission pathway used by C. parvum. Secondary anthroponotic transmission of C. parvum remains possible among close contacts of zoonotic cases. Ongoing 14-day quarantine measures for new arrivals to New Zealand have likely suppressed new incursions of C. hominis from overseas. Our findings suggest that C. hominis may be controlled or even eradicated through nonpharmaceutical interventions.

Indexed as

SARS-CoV-2AnimalsCOVID-19CryptosporidiosisCryptosporidiumFecesHumansNew ZealandZoonosesCovid-19CryptosporidiumNew Zealandnonpharmaceutical interventionpublic health

Identifiers

PMID34120663
PMCPMC8383192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.