ArticleGenome biology2021
Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes.
Article in Genome biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- predNMD: prediction of nonsense-mediated mRNA decay for improved clinical variant pathogenicity classification.bioRxiv : the preprint server for biology · 2026Article
- Genetic variants reshape the mScientific reports · 2025Article
- m6A modification is incorporated into bacterial mRNA without specific functional benefit.Nucleic acids research · 2025Article
- Genome-wide profiling of N6-methyladenosine-modified pseudogene-derived long noncoding RNAs reveals the tumour-promoting and innate immune-restraining function of RPS15AP12 in ovarian cancer.Clinical and translational medicine · 2025Article
- Epigenetic regulation in female reproduction: the impact of m6A on maternal-fetal health.Cell death discovery · 2025Review
- Exploring the impact of mFrontiers in immunology · 2024Review
- Leveraging a disulfidptosis-based signature to improve the survival and drug sensitivity of bladder cancer patients.Frontiers in immunology · 2023Article
- Pseudogenes and Liquid Phase Separation in Epigenetic Expression.Frontiers in oncology · 2022Review
- N6-methyladenosine-associated prognostic pseudogenes contribute to predicting immunotherapy benefits and therapeutic agents in head and neck squamous cell carcinoma.Theranostics · 2022Article
- Development and validation of a mFrontiers in oncology · 2022Article
- N6-Methyladenosine Modifications in the Female Reproductive System: Roles in Gonad Development and Diseases.International journal of biological sciences · 2022Review
- Functional Micropeptides Encoded by Long Non-Coding RNAs: A Comprehensive Review.Frontiers in molecular biosciences · 2022Review
- N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner.Bioengineered · 2022Article
- Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes.Genome biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCanonical nonsense-mediated decay (NMD) is an important splicing-dependent process for mRNA surveillance in mammals. However, processed pseudogenes are not able to trigger NMD due to their lack of introns. It is largely unknown whether they have evolved other surveillance mechanisms.
resultsHere, we find that the RNAs of pseudogenes, especially processed pseudogenes, have dramatically higher m
conclusionsOur discovery reveals a novel evolutionary role of m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.