Evidence map›Paper›PMID 34120616›Full record

Trial reportMalaria journal2021

Use of the creating opportunities for parent empowerment programme to decrease mental health problems in Ugandan children surviving severe malaria: a randomized controlled trial.

Paul Bangirana, Annet Birabwa, Mary Nyakato, Ann J Nakitende, Maria Kroupina, John M Ssenkusu, Noeline Nakasujja, Seggane Musisi, Chandy C John, Richard Idro

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03432039 (Preventing Long-term Mental Health Problems in Children Admitted With Severe Malaria at Naguru General Hospital in Uganda), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03432039 nacompletednot on this map

Preventing Long-term Mental Health Problems in Children Admitted With Severe Malaria at Naguru General Hospital in Uganda

TypeinterventionalSponsorMakerere UniversityRan2018 to 2019Enrolled120ConditionsMalariaArmsPsychoeducation, Behavioral
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Association between Maternal Anxiety and Children's Problem Behaviors: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Paul BangiranaDepartment of Psychiatry, Makerere University College of Health Sciences, Kampala, Uganda. pbangirana@yahoo.com.ORCID http://orcid.org/0000-0002-7136-0594
Annet BirabwaDepartment of Mental Health and Community Psychology, Makerere University College of Humanities and Social Sciences, Kampala, Uganda.
Mary NyakatoDepartment of Psychiatry, Makerere University College of Health Sciences, Kampala, Uganda.
Ann J NakitendeDepartment of Psychiatry, Makerere University College of Health Sciences, Kampala, Uganda.
Maria KroupinaDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
John M SsenkusuDepartment of Epidemiology and Biostatistics, Makerere University College of Health Sciences, Kampala, Uganda.
Noeline NakasujjaDepartment of Psychiatry, Makerere University College of Health Sciences, Kampala, Uganda.
Seggane MusisiDepartment of Psychiatry, Makerere University College of Health Sciences, Kampala, Uganda.
Chandy C JohnRyan White Center for Pediatric Infectious Disease and Global Health, Indiana University, Indianapolis, IN, USA.
Richard IdroDepartment of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.
Makerere University · UGIndiana University Health · USUniversity of Minnesota · US

Funding

Severe Malaria And Risk to The Brain (SMART Brain)R01NS055349 · NINDS · UNIVERSITY OF MINNESOTA · PI Chandy C. John, Ruth Namazzi · 2008 to 2026
$11.2M
NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
FIC NIH HHS D43 TW010132NIH HHS D43TW010132NIH HHS R01NS055349NINDS NIH HHS R01 NS055349
6 · The paper itself

Abstract

backgroundSevere malaria is associated with long-term mental health problems in Ugandan children. This study investigated the effect of a behavioural intervention for caregivers of children admitted with severe malaria, on the children's mental health outcomes 6 months after discharge.

methodsThis randomized controlled trial was conducted at Naguru Hospital in Kampala, Uganda from January 2018 to July 2019. Caregiver and child dyads were randomly assigned to either a psycho-educational arm providing information about hospital procedures during admission (control group), or to a behavioural arm providing information about the child's possible emotions and behaviour during and after admission, and providing age appropriate games for the caregiver and child (intervention group). Pre- and post-intervention assessments for caregiver anxiety and depression (Hopkins Symptom Checklist) and child mental health problems (Strength and Difficulties Questionnaire and the Child Behaviour Checklist) were done during admission and 6 months after discharge, respectively. T-tests, analysis of covariance, Chi-Square, and generalized estimating equations were used to compare outcomes between the two treatment arms.

resultsThere were 120 caregiver-child dyads recruited at baseline with children aged 1.45 to 4.89 years (mean age 2.85 years, SD = 1.01). The intervention and control groups had similar sociodemographic, clinical and behavioural characteristics at baseline. Caregiver depression at baseline, mother's education and female child were associated with behavioural problems in the child at baseline (p < 0.05). At 6 months follow-up, there was no difference in the frequency of behavioural problems between the groups (6.8% vs. 10% in intervention vs control groups, respectively, p = 0.72). Caregiver depression and anxiety scores between the treatment arms did not differ at 6 months follow-up.

conclusionThis behavioural intervention for caregivers and their children admitted with severe malaria had no effect on the child's mental health outcomes at 6 months. Further studies need to develop interventions for mental health problems after severe malaria in children with longer follow-up time. Trail registration ClinicalTrials.gov Identifier: NCT03432039.

Indexed as

EmpowermentBehavior TherapyCaregiversChild HealthChild, PreschoolHumansInfantMental HealthParentsUgandaBehavioural problemsCaregiver trainingMental healthSevere malaria

Identifiers

PMID34120616
PMCPMC8201864
OpenAlexW3166192889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.