ArticleMedical decision making : an international journal of the Society for Medical Decision Making2022
A Simple Method for Simulating Dementia Onset and Death within an Existing Demographic Model.
Article in Medical decision making : an international journal of the Society for Medical Decision Making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Investment in Alzheimer's disease research for the next generation of adults with Down syndrome will yield health benefits for future generations.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Projected Demographic Trends in the Likelihood of Having or Becoming a Dementia Family Caregiver in the U.S. Through 2060.Populations · 2025Article
- Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe.BMJ open · 2022Article
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5 authors.
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Abstract
backgroundDementia is a common disease that has an impact on both the affected individual and family members who provide caregiving. Simulation models can assist in setting policy that anticipates public health needs by predicting the demand for and availability of care.
objectiveWe developed a relatively simple method for simulating the onset of dementia that can be used in combination with an existing microsimulation model.
methodsWe started with Socsim, a demographic microsimulation model that simulates a population with family kinship networks. We simulated dementia in the Socsim population by simulating the number of individuals diagnosed with dementia in their lifetime and the ages of onset and death from dementia for each of these dementia cases. We then matched dementia cases to the simulated population based on age at death, so for each individual, we simulate whether they develop dementia and, if so, their age at onset. This approach simulates dementia onset but does not alter the demographic model's simulated age of death.
resultsWe selected model dementia parameters so that the combined Socsim-Dementia model reproduces published dementia prevalence rates and survival times after diagnosis.
conclusionsAdding simulation of dementia to a kinship network model enables prediction of the availability of family caregivers for people with dementia under a range of different assumptions about future fertility, mortality, and dementia risk. We demonstrated how to add simulation of dementia onset and death to an existing microsimulation model to obtain a method for predicting dementia prevalence in the context of another more detailed model. The approach we developed can be generalized to simulate other progressive health conditions that affect mortality.
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