ArticleJournal of the American Heart Association2021
Causal Effect of Adiposity Measures on Blood Pressure Traits in 2 Urban Swedish Cohorts: A Mendelian Randomization Study.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies.BMC medicine · 2021Pooled it
- Serum calcium, even within normal range, is associated with blood pressure with a potential influence of calcium intake.Journal of the Endocrine Society · 2026Article
- Ambient air and noise pollution effect on cardiovascular health risk and lifestyle intervention to attenuate it: study protocol for a randomized clinical trial.Frontiers in public health · 2026Article
- Physical Activity and Favorable Adiposity Genetic Liability Reduce the Risk of Hypertension Among High Body Mass Individuals.Journal of the American Heart Association · 2025Article
- Association of Visceral Adipose Tissue With Hypertension: Results From the NHANES 2011-2018 and Mendelian Randomization Analyses.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Using Machine Learning to Evaluate the Value of Genetic Liabilities in the Classification of Hypertension within the UK Biobank.Journal of clinical medicine · 2024Article
- Physical activity alters the effect of genetic determinants of adiposity on hypertension among individuals of European ancestry in the UKB.Scandinavian journal of medicine & science in sports · 2024Article
- Surrogate Adiposity Markers and Mortality.JAMA network open · 2023Article
- Association of Thyroid Function with Blood Pressure and Cardiovascular Disease: A Mendelian Randomization.Journal of personalized medicine · 2021Article
- Causal Effect of Adiposity Measures on Blood Pressure Traits in 2 Urban Swedish Cohorts: A Mendelian Randomization Study.Journal of the American Heart Association · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
Abstract
Background Different adiposity traits may be causally related to hypertension in different ways. By using genetic variants as randomly allocated proxies for studying the effect of modifying adiposity traits, the Mendelian randomization approach can be used to investigate this. Methods and Results In this study, we used 4 different genetic risk scores (GRS; GRS-BMI
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.