ArticleNeurogastroenterology and motility2022
Validation of secondary peristalsis classification using FLIP panometry in 741 subjects undergoing manometry.
Article in Neurogastroenterology and motility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Normative values for esophageal functional lumen imaging probe measurements: A meta-analysis.Neurogastroenterology and motility · 2022Pooled it
- Accuracy of Novice Raters for Esophageal Motility Classifications Using Functional Lumen Imaging Probe Panometry.Neurogastroenterology and motility · 2026Article
- Validation of Functional Lumen Imaging Probe Panometry Esophageal Motility Classification Version 2.0: A Study of 805 Patients.Neurogastroenterology and motility · 2025Article
- Improved Performance of an Updated Artificial Intelligence Model for Interpretation of Functional Lumen Imaging Probe Panometry Studies.Neurogastroenterology and motility · 2025Article
- Subjective Assessment of the Pyloric Sphincter During Endoscopy and Its Correlation with FLIP Panometry.Digestive diseases and sciences · 2025Article
- Assessing Treatment Outcomes in Achalasia Using 4-Dimensional High-resolution Impedance Manometry.Journal of neurogastroenterology and motility · 2025Article
- Functional Lumen Imaging Probe Panometry.Gastrointestinal endoscopy clinics of North America · 2025Review
- The conundrum of esophagogastric junction outflow obstruction: Answers to key clinical questions.Annals of the New York Academy of Sciences · 2025Review
- Endoscopic Prediction of Achalasia: Putting the CART Before the CARS.Neurogastroenterology and motility · 2025Article
- A Standardized Approach to Performing and Interpreting Functional Lumen Imaging Probe Panometry for Esophageal Motility Disorders: The Dallas Consensus.Gastroenterology · 2025Article
- The functional lumen imaging probe contractile response pattern is the best predictor of botulinum toxin response in esophagogastric junction outflow obstruction.Neurogastroenterology and motility · 2024Article
- Effects of Cholecystokinin on Esophageal Motor Response to Distension in Asymptomatic Volunteers.Journal of neurogastroenterology and motility · 2024Article
- Functional lumen imaging probe use in a high-volume practice: Practical and technical implications.World journal of gastrointestinal endoscopy · 2024Article
- Composite score of physiomechanical esophageal function using functional lumen imaging probe panometry in eosinophilic esophagitis.Gastrointestinal endoscopy · 2024Article
- Secondary peristalsis and esophagogastric junction distensibility in symptomatic post-fundoplication patients.Neurogastroenterology and motility · 2024Article
- Presence of esophageal contractility after achalasia treatment is associated with improved esophageal emptying.Neurogastroenterology and motility · 2024Article
- Impedance planimetry and panometry (EndoFLIP™) can replace manometry in preoperative anti-reflux surgery assessment.Surgical endoscopy · 2024Article
- Compartmentalized pressurization is a novel prognostic factor for hypercontractile esophagus.Neurogastroenterology and motility · 2024Article
- Functional lumen imaging probe topography identifies patients with normal acid exposure and esophageal hypervigilance amongst proton-pump inhibitor non-responders.Surgical endoscopy · 2024Article
- Assessing mechanical function of peristalsis with functional lumen imaging probe panometry: Contraction power and displaced volume.Neurogastroenterology and motility · 2023Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
aimsThis study aimed to systematically evaluate a classification scheme of secondary peristalsis using functional luminal imaging probe (FLIP) panometry through comparison with primary peristalsis on high-resolution manometry (HRM).
methods706 adult patients that completed FLIP and HRM for primary esophageal motility evaluation and 35 asymptomatic volunteers ("controls") were included. Secondary peristalsis, that is, contractile responses (CRs), was classified on FLIP panometry by the presence and pattern of contractility as normal (NCR), borderline (BCR), impaired/disordered (IDCR), absent (ACR), or spastic-reactive (SRCR). Primary peristalsis on HRM was assessed according to the Chicago Classification.
resultsAll 35 of the controls had antegrade contractions on FLIP panometry with either NCR (89%) or BCR (11%). The average percentages of normal swallows on HRM varied across contractile response patterns from 84% in NCR, 68% in BCR, 39% in IDCR, to 11% in ACR, as did the percentage of failed swallows on HRM: 4% in NCR, 12% in BCR, 36% in IDCR, and 79% in ACR. SRCR on FLIP panometry was observed in 18/57 (32%) patients with type III achalasia, 4/15 (27%) with distal esophageal spasm, and 7/15 (47%) with hypercontractile esophagus on HRM.
conclusionsThe FLIP panometry contractile response patterns reflect a pathophysiologic transition from normal to abnormal esophageal peristaltic function with shared features with primary peristaltic function/dysfunction on HRM. Thus, these patterns of the contractile response to distension can facilitate the evaluation of esophageal motility using FLIP panometry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.