Evidence map›Paper›PMID 34120250›Full record

ArticleInflammopharmacology2021

Effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension-in vivo.

Folake Lucy Oyetayo, Seun Funmilola Akomolafe, Gbemisola Beulah Balogun

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effect ofJournal of diabetes and metabolic disorders · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Folake Lucy OyetayoDepartment of Biochemistry, Faculty of Science, Ekiti State University, Ekiti State, P.M.B. 5363, Ado Ekiti, Nigeria.
Seun Funmilola AkomolafeDepartment of Biochemistry, Faculty of Science, Ekiti State University, Ekiti State, P.M.B. 5363, Ado Ekiti, Nigeria. purposefulseun@yahoo.co.uk.ORCID https://orcid.org/0000-0002-7061-8303
Gbemisola Beulah BalogunDepartment of Biochemistry, Faculty of Science, Ekiti State University, Ekiti State, P.M.B. 5363, Ado Ekiti, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension in vivo were determined. Feeding with supplemented diet with pulp reduced heart rate, mean arterial pressure, systolic and diastolic blood pressure levels of hypertensive-treated groups. Moreover, hypertensive-treated groups fed with fruit pulp supplemented diets had significantly (p < 0.05) lower level of serum pro-inflammatory markers when compared to untreated hypertensive group. Furthermore, feeding with supplemented diet with pulp and captopril administration reduced AChE, BChE, ACE, and arginase activities of hypertensive-treated groups. The fruit pulp supplemented diet also increased antioxidant status of hypertensive-treated groups. This was supported by the histopathological examination of the kidney and heart tissues. These beneficial effects could in part be the explanations of ethnomedicinal uses of the fruit pulp in the management of hypertension. Nevertheless, the higher percentage inclusion of the pulp showed higher antihypertensive effects.

Indexed as

FruitSapotaceaeAnimalsAntihypertensive AgentsAntioxidantsHemodynamicsHypertensionInflammation MediatorsMalePlant ExtractsRatsRats, WistarAntihypertensive AgentsAntioxidantsInflammation MediatorsPlant ExtractsBlood pressureChrysophyllum albidumCyclosporineDietary supplementsHypertensionInflammation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.