ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Risk factors for acute kidney injury in neonates with congenital diaphragmatic hernia.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06050525 (Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia
Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Comparison of creatinine- and cystatin C-based definitions of acute kidney injury in neonates with congenital diaphragmatic hernia.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Incidence of and risk factors for acute kidney injury in neonates with congenital diaphragmatic hernia.European journal of pediatrics · 2025Article
- Expanded discussion of kidney health monitoring for critically ill term and late preterm infants after acute kidney injury: a report from the Neonatal Kidney Health Consensus Workshop.Pediatric nephrology (Berlin, Germany) · 2025Article
- Article
- Arterial hypertension in infants with congenital diaphragmatic hernia following surgical repair.European journal of pediatrics · 2024Article
- Acute kidney injury in infants diagnosed with congenital diaphragmatic hernia.Pediatric research · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine incidence of acute kidney injury (AKI), antenatal and postnatal predictors, and impact of AKI on outcomes in infants with congenital diaphragmatic hernia (CDH). STUDY
designSingle center retrospective study of 90 CDH infants from 2009-2017. Baseline characteristics, CDH severity, possible AKI predictors, and clinical outcomes were compared between infants with and without AKI.
resultIn total, 38% of infants developed AKI, 44% stage 1, 29% stage 2, 27% stage 3. Lower antenatal lung volumes and liver herniation were associated with AKI. Extracorporeal life support (ECLS), diuretics, abdominal closure surgery, hypotension, and elevated plasma free hemoglobin were associated with AKI. Overall survival was 79%, 47% with AKI, and 35% with AKI on ECLS. AKI is associated with increased mechanical ventilation duration and length of stay.
conclusionAKI is common among CDH infants and associated with adverse outcomes. Standardized care bundles addressing AKI risk factors may reduce AKI incidence and severity.
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Registered trials
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