Evidence map›Paper›PMID 34119504›Full record

ArticleUrology2021

5-Item Modified Frailty Index as a Preoperative Predictor of Morbidity Following Minimally Invasive Partial Nephrectomy.

Jordan Goldwag, Andrew Harris, Amber D Bettis

Abstract read
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In one paragraph

Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Predictive Ability of Comorbidity Indices for Surgical Morbidity and Mortality: a Systematic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Pooled it
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  4. Frailty and nutritional status predict postoperative complications in radical cystectomy patients.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
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  14. The geriatric nutritional risk index predicts complications after nephrectomy for renal cancer.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jordan GoldwagDepartment of Urology; University of Kentucky; Lexington, KY. Electronic address: jgo285@uky.edu.
Andrew HarrisDepartment of Urology; University of Kentucky; Lexington, KY; Department of Urology; University of Kentucky; Lexington, KY.
Amber D BettisDepartment of Surgery; University of Kentucky; Lexington, KY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo apply the modified frailty index-5 (mFI-5) to those patients undergoing minimally invasive partial nephrectomy (MIPN) to examine the relationship between frailty and postoperative outcomes.

methodsUsing the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database, data were retrospectively reviewed between 2012 and 2018 for cases coded for MIPN. The mFI-5 score was defined on a scale of 1 to 5, with each patient receiving one point per each of the following comorbidities: congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), diabetes mellitus, hypertension that requires medication and functional health status of partial or total dependence prior to surgery. Complications were examined within the first 30 days postoperatively. Using univariate and multivariate logistic regression, postoperative outcomes were obtained and stratified based on frailty score.

resultsOf the 18,904 cases identified between 2012 and 2018, mFI-5 score was 0 for 38.0% of patients, 1 for 42.8%, ≥2 for 19.2%. With increasing mFI-5 score, a significant increase in multiple postoperative morbidities were identified (P <0.05). 11.2% of patients with mFI-5 ≥2 had complications vs 5.3% with mFI-5 of 0 and 7.8% mFI-5 of 1, P <0.05. Multivariate analysis revealed nearly 50% increase in the odds of having an overall complication for patients with mFI-5 score ≥2 (OR = 1.48, 95% CI 1.22 - 1.80, P <0.001).

conclusionThe mFI-5 is a well defined and easily ascertainable predictor of postoperative outcomes in those undergoing MIPN and could be used preoperatively to identify and counsel those at increased risk for morbidity.

Indexed as

Severity of Illness IndexAgedComorbidityDatabases, FactualDiabetes MellitusFemaleFrailtyHealth StatusHeart FailureHumansHypertensionMaleMiddle AgedMinimally Invasive Surgical ProceduresNephrectomyPostoperative Complications

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.