Evidence map›Paper›PMID 34119443›Full record

ArticleBrazilian journal of physical therapy

A randomised controlled trial of implementation of a guideline-based clinical pathway of care to improve health outcomes following whiplash injury (Whiplash ImPaCT): Statistical analysis plan.

Michele Sterling, Trudy Rebbeck, Luke B Connelly, Andrew Leaver, Carrie Ritchie, Aila Bandong, Martin Mackey, Ian D Cameron, Geoffrey Mitchell, Mohit Arora and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of physical therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Michele SterlingRECOVER Injury Research Centre, NHMRC CRE in Road Traffic Injury Recovery, The University of Queensland, Australia. Electronic address: m.sterling@uq.edu.au.
Trudy RebbeckFaculty of Health Sciences, Discipline of Physiotherapy, University of Sydney, New South Wales, Australia.
Luke B ConnellyCentre for Business and Economics of Health, The University of Queensland, Australia; and Faculty of Economics and Statistics, The University of Bologna, Italy.
Andrew LeaverFaculty of Health Sciences, Discipline of Physiotherapy, University of Sydney, New South Wales, Australia.
Carrie RitchieRECOVER Injury Research Centre, NHMRC CRE in Road Traffic Injury Recovery, The University of Queensland, Australia.
Aila BandongFaculty of Health Sciences, Discipline of Physiotherapy, University of Sydney, New South Wales, Australia; College of Allied Medical Professions, The University of the Philippines Manila, Philippines.
Martin MackeyFaculty of Health Sciences, Discipline of Physiotherapy, University of Sydney, New South Wales, Australia.
Ian D CameronJohn Walsh Centre for Rehabilitation Research, Kolling Institute of Medical Research, Royal North Shore Hospital, New South Wales, Australia; Faculty of Medicine and Health, Sydney Medical School - Northern, The University of Sydney, New South Wales, Australia.
Geoffrey MitchellDiscipline of General Practice, School of Medicine, University of Queensland, Queensland, Australia.
Mohit AroraJohn Walsh Centre for Rehabilitation Research, Kolling Institute of Medical Research, Royal North Shore Hospital, New South Wales, Australia; Faculty of Medicine and Health, Sydney Medical School - Northern, The University of Sydney, New South Wales, Australia.
Nigel R ArmfieldRECOVER Injury Research Centre, NHMRC CRE in Road Traffic Injury Recovery, The University of Queensland, Australia; Centre for Health Services Research, Faculty of Medicine, The University of Queensland, Australia.
University of Sydney · AUUniversity of Queensland · AUNational Health and Medical Research Council · AUNorthern Sydney Local Health District · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStatistical analysis plans describe the processes of data handling and analysis in clinical trials; by doing so they increase the transparency of the analysis and reporting of studies. This paper reports the planned statistical analysis plan for the Whiplash ImPaCT study. For individuals with whiplash injury, Whiplash ImPaCT aims to assess the effectiveness of a guidelines-based clinical pathway of care compared with usual care.

methodsWe report the planned procedures, methods, and reporting for the primary and secondary analyses of the Whiplash ImPaCT study. The primary outcomes are Global Recovery and Neck Disability Index at 3 months post-randomisation. Outcomes will be analysed according to the intention to treat principle using linear mixed models. A cost-utility analysis will be conducted to compute the incremental cost-effectiveness of the intervention to usual care. We describe data handling, our analytical approach, assumptions about missing data, and our planned methods of reporting. DISCUSSION: This paper will provide a detailed description of the planned analyses for the Whiplash ImPaCT trial.

Indexed as

Cost-Benefit AnalysisWhiplash InjuriesCritical PathwaysHumansOutcome Assessment, Health CarePain MeasurementClinical pathwayRandomised clinical trialWhiplash associated disorders

Identifiers

PMID34119443
PMCPMC8353303
OpenAlexW3171411598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.