Evidence map›Paper›PMID 34119064›Full record

ArticleLancet (London, England)2021

Inclusion and diversity in the PRINCIPLE trial.

Mahendra G Patel, Jienchi Dorward, Ly-Mee Yu, Fd Richard Hobbs, Christopher C Butler, PRINCIPLE Trial Collaborative Group

Erratum issuedAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Lancet (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Colchicine for COVID-19 in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Trial
  4. Article
  5. Precision Prevention Studies: A Targeted Approach to Cancer Prevention.Cancer prevention research (Philadelphia, Pa.) · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Mahendra G PatelNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK; School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.
Jienchi DorwardNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
Ly-Mee YuNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.
Fd Richard HobbsNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.
Christopher C ButlerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK. Electronic address: principle@phc.ox.ac.uk.
PRINCIPLE Trial Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cultural DiversityHumans

Identifiers

PMID34119064
PMCPMC9752781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.