Evidence map›Paper›PMID 34118962›Full record

ArticleGut pathogens2021

A re-testing range is recommended for

Xiangyu Wang, Shuzhen Zhang, Eng Guan Chua, Yongsheng He, Xiaofeng Li, Aijun Liu, Haiting Chen, Michael J Wise, Barry J Marshall, Dayong Sun and 2 more

Open access · goldAbstract read
In one paragraph

Article in Gut pathogens, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Urea breath test forWorld journal of gastroenterology · 2024
    Pooled it
  2. Article
  3. Association ofFrontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. Article
  6. Nine-year risk stratification and prediction ofFrontiers in public health · 2025
    Article
  7. Article
  8. Evaluation of urea breath test as a diagnostic tool forWorld journal of gastroenterology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Xiangyu Wang *Department of Gastroenterology, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Shuzhen Zhang *Department of Clinical Laboratory, Kuichong People's Hospital, Shenzhen, 518116, China.
Eng Guan ChuaThe Marshall Centre for Infectious Diseases Research and Training, University of Western Australia, Perth, 6009, Australia.
Yongsheng HeDepartment of Gastroenterology, Kuichong People's Hospital, Shenzhen, 518116, China.
Xiaofeng LiDepartment of Nuclear Medicine, Shenzhen People's Hospital, Shenzhen, 518001, China.
Aijun LiuDepartment of Gastroenterology, Kuichong People's Hospital, Shenzhen, 518116, China.
Haiting ChenDepartment of Clinical Laboratory, Kuichong People's Hospital, Shenzhen, 518116, China.
Michael J WiseThe Marshall Centre for Infectious Diseases Research and Training, University of Western Australia, Perth, 6009, Australia.
Barry J MarshallThe Marshall Centre for Infectious Diseases Research and Training, University of Western Australia, Perth, 6009, Australia.
Dayong SunDepartment of Gastroenterology, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Xuehong LiDepartment of Clinical Laboratory, Kuichong People's Hospital, Shenzhen, 518116, China. lihongsz@163.com.
Chin Yen TayThe Marshall Centre for Infectious Diseases Research and Training, University of Western Australia, Perth, 6009, Australia. alfred.tay@uwa.edu.au.ORCID http://orcid.org/0000-0001-9705-4010
The University of Western Australia · AUShenZhen People’s Hospital · CNShenzhen Second People's Hospital · CN

Funding

National Natural Science Foundation of China 81902022Sanming Project of Medicine in Shenzhen SZSM201510050
6 · The paper itself

Abstract

backgroundThe urea breath test (UBT) is widely used for diagnosing Helicobacter pylori infection. In the Shenzhen Kuichong People's Hospital, some UBT findings were contradictory to the histology outcomes, therefore this study aimed to assess and compare the diagnostic performance of both

methodsWe recruited 484 H. pylori-treatment naïve patients, among which 217 and 267 were tested by the

resultsIn patients who were tested using the

conclusionsThe establishment of an indeterminate range is recommended to allow for repeated testing to confirm H. pylori infection, and thereby avoiding unnecessary antibiotic treatment.

trial registrationChinese Clinical Trial Registry, ChiCTR2000041570. Registered 29 December 2020- Retrospectively registered, http://www.chictr.org.cn/edit.aspx?pid=66416&htm=4.

Indexed as

Diagnostic performanceHelicobacter pyloriIndeterminate rangeUrea breath test

Identifiers

PMID34118962
PMCPMC8199820
OpenAlexW3168112538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.