ArticleMalaria journal2021
Low MSP-1 haplotype diversity in the West Palearctic population of the avian malaria parasite Plasmodium relictum.
Article in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Avian haemosporidian parasite prevalence and diversity in two populations of the American kestrel (Falco sparverius).Parasitology research · 2025Article
- Imprudent use of MalAvi names biases the estimation of parasite diversity of avian haemosporidians.PLoS pathogens · 2025Article
- HiddenCurrent research in parasitology & vector-borne diseases · 2025Article
- Genomic variation in Plasmodium relictum (lineage SGS1) and its implications for avian malaria infection outcomes: insights from experimental infections and genome-wide analysis.Malaria journal · 2024Article
- Genomic sequence capture of Plasmodium relictum in experimentally infected birds.Parasites & vectors · 2022Article
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Authors and funding
11 authors at 5 institutions in 7 countries.
Funding
Abstract
backgroundAlthough avian Plasmodium species are widespread and common across the globe, limited data exist on how genetically variable their populations are. Here, the hypothesis that the avian blood parasite Plasmodium relictum exhibits very low genetic diversity in its Western Palearctic transmission area (from Morocco to Sweden in the north and Transcaucasia in the east) was tested.
methodsThe genetic diversity of Plasmodium relictum was investigated by sequencing a portion (block 14) of the fast-evolving merozoite surface protein 1 (MSP1) gene in 75 different P. relictum infections from 36 host species. Furthermore, the full-length MSP1 sequences representing the common block 14 allele was sequenced in order to investigate if additional variation could be found outside block 14.
resultsThe majority (72 of 75) of the sequenced infections shared the same MSP1 allele. This common allele has previously been found to be the dominant allele transmitted in Europe.
conclusionThe results corroborate earlier findings derived from a limited dataset that the globally transmitted malaria parasite P. relictum exhibits very low genetic diversity in its Western Palearctic transmission area. This is likely the result of a recent introduction event or a selective sweep.
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