Evidence map›Paper›PMID 34118932›Full record

ArticleHealth and quality of life outcomes2021

Validation of a novel online depression symptom severity rating scale: the R8 Depression.

Yuki Takao, Eduardo Figueroa, Kevin Fernand Jean Berna, Youjin Jo, Lee Andrew Kissane, Kimio Yoshimura, Richard Tranter, Richard J Porter

Open access · goldAbstract readValidation Study
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 6 countries.

Yuki TakaoTower Hamlets Centre for Mental Health, Bancroft Rd, London, E1 4DG, UK.
Eduardo FigueroaAmerican Clinic Tokyo, Niikura Building 3F, 1-7-4 Akasaka, Minato, Tokyo, 107-0052, Japan.
Kevin Fernand Jean BernaUniversity of Luxembourg, 2, avenue de l'Université, 4365, Esch-sur-Alzette, Luxembourg.
Youjin JoOregon State University, 1500 SW Jefferson St., Corvallis, OR, 97331, USA.
Lee Andrew KissaneAmerican Clinic Tokyo, Niikura Building 3F, 1-7-4 Akasaka, Minato, Tokyo, 107-0052, Japan. andrew@tokyomentalhealth.com.
Kimio YoshimuraDepartment of Health Policy and Management, Keio University School of Medicine, Tokyo, Japan.
Richard TranterMid North Coast Local Health District Mental Health Services, Port Macquarie, NSW, 2444, Australia.
Richard J PorterDepartment of Psychological Medicine, University of Otago, Christchurch, New Zealand.
FrontLine Service · USKeio University · JPLondon Borough of Tower Hamlets · GBOregon State University · USUniversity of Luxembourg · LUUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn automated web-based assessment and monitoring system ( www.psynary.com ) has been developed to assist non-specialist clinicians in managing common mood and anxiety disorders. Psynary promotes the use of standardised outcome measures to assess symptom severity and optimise treatments with the aim of improving outcomes and enabling faster recovery. This paper analyses the results from two parallel studies in New Zealand and Japan (OptiMA-1 NZ and Japan) to assess the validity of the R8 Depression scale, one of the system's core outcome measures.

methodsClinical samples were recruited from a public secondary care and a private psychiatry clinic. Participants completed the outcome measures for the study via the online Psynary system. The R8 Depression scale is a 30-item questionnaire which includes all symptom domains covered in the ICD-10 classification of depression. The Patient Health Questionnaire (PHQ-9) was completed at the same time points as the R8 Depression, with a smaller sample also completing a paper-based Quick Inventory of Depressive Symptomatology (QIDS-SR16). Internal validity was quantified via Cronbach's alpha and Guttman lower bounds method. External validation against the PHQ-9 and QIDS used the Pearson's and Kendall's correlation coefficients. Severity categories were set using a multivariate regression model.

results270 patients participated in the study and completed a maximum of 1 baseline and 5 reviews within a 90-day period, giving a total of 1124 assessments with the PHQ-9 also being completed in 1053 of these assessments. R8 Depression normative data was also collected from 204 non-clinical volunteers with 187 of these also completing the PHQ9. Internal reliability scores were all higher than 0.9 (n = 1328). There was overall good external validity when comparing the R8 Depression to the PHQ-9, with a correlation of 0.91 for the combined normative and clinical samples (n = 1240).

conclusionsThe R8 Depression has been developed as a patient-rated outcome measure for depression for administration on an online system called "Psynary". It has high internal and external validity against current widely used scales. Further work is underway to determine the sensitivity to change of the R8 Depression.

Indexed as

AdultDepressionHumansJapanMaleMiddle AgedNew ZealandPatient Health QuestionnairePsychiatric Status Rating ScalesPsychometricsQuality of LifeReproducibility of ResultsResearch DesignDepressione-mental healthMood disorderOutcome measurePatient-ratedQuestionnaireScaleSelf-reportValidation

Identifiers

PMID34118932
PMCPMC8196428
OpenAlexW3170325289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.