Evidence map›Paper›PMID 34118912›Full record

ArticleBMC public health2021

HIV and cardiovascular disease in sub-Saharan Africa: Demographic and Health Survey data for 4 countries.

Leonard E Egede, Rebekah J Walker, Patricia Monroe, Joni S Williams, Jennifer A Campbell, Aprill Z Dawson

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leonard E EgedeDepartment of Medicine, Division of General Internal Medicine, Froedtert & The Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226-3596, USA. legede@mcw.edu.
Rebekah J WalkerDepartment of Medicine, Division of General Internal Medicine, Froedtert & The Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226-3596, USA.
Patricia MonroeCenter for Advancing Population Science, Medical College of Wisconsin, Milwaukee, WI, USA.
Joni S WilliamsDepartment of Medicine, Division of General Internal Medicine, Froedtert & The Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226-3596, USA.
Jennifer A CampbellDepartment of Medicine, Division of General Internal Medicine, Froedtert & The Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226-3596, USA.
Aprill Z DawsonDepartment of Medicine, Division of General Internal Medicine, Froedtert & The Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226-3596, USA.
Medical College of Wisconsin · US

Funding

HOME DM-BAT: Home-based Diabetes-Modified Behavioral Activation Treatment for Low Income Seniors with T2DM Diversity SupplementR01DK118038 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EGEDE, LEONARD E. · 2019 to 2023
$3.5M
Financial Incentives And Nurse Coaching to Enhance Diabetes Outcomes (FINANCE-DM) - Diversity SupplementR01DK120861 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EGEDE, LEONARD E. · 2019 to 2023
$3.4M
Lowering the Impact of Food insecurity in African American Adults with Type 2 Diabetes Mellitus (LIFT-DM) - Diversity SupplementR01MD013826 · NIMHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EGEDE, LEONARD E., WALKER, REBEKAH J · 2019 to 2023
$3.4M
Technology Intensified Diabetes Education Study in AA with T2DM (TIDES)K24DK093699 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI EGEDE, LEONARD E. · 2011 to 2020
$1.5M
NIDDK NIH HHS K24 DK093699NIDDK NIH HHS R01 DK118038NIDDK NIH HHS R01 DK120861NIMHD NIH HHS R01 MD013826
6 · The paper itself

Abstract

backgroundInvestigate the relationship between two common cardiovascular diseases and HIV in adults living in sub-Saharan Africa using population data provided through the Demographic and Health Survey.

methodsData for four sub-Saharan countries were used. All adults asked questions regarding diagnosis of HIV, diabetes, and hypertension were included in the sample totaling 5356 in Lesotho, 3294 in Namibia, 9917 in Senegal, and 1051 in South Africa. Logistic models were run for each country separately, with self-reported diabetes as the first outcome and self-reported hypertension as the second outcome and HIV status as the primary independent variable. Models were adjusted for age, gender, rural/urban residence and BMI. Complex survey design allowed weighting to the population.

resultsPrevalence of self-reported diabetes ranged from 3.8% in Namibia to 0.5% in Senegal. Prevalence of self-reported hypertension ranged from 22.9% in Namibia to 0.6% in Senegal. In unadjusted models, individuals with HIV in Lesotho were 2 times more likely to have self-reported diabetes (OR = 2.01, 95% CI 1.08-3.73), however the relationship lost significance after adjustment. Individuals with HIV were less likely to have self-reported diabetes after adjustment in Namibia (OR = 0.29, 95% CI 0.12-0.72) and less likely to have self-reported hypertension after adjustment in Lesotho (OR = 0.63, 95% CI 0.47-0.83). Relationships were not significant for Senegal or South Africa. DISCUSSION: HIV did not serve as a risk factor for self-reported cardiovascular disease in sub-Saharan Africa during the years included in this study. However, given the growing prevalence of diabetes and hypertension in the region, and the high prevalence of undiagnosed cardiovascular disease, it will be important to continue to track and monitor cardiovascular disease at the population level and in individuals with and without HIV.

conclusionsThe odds of self-reported diabetes in individuals with HIV was high in Lesotho and low in Namibia, while the odds of self-reported hypertension in individuals with HIV was low across all 4 countries included in this study. Programs are needed to target individuals that need to manage multiple diseases at once and should consider increasing access to cardiovascular disease management programs for older adults, individuals with high BMI, women, and those living in urban settings.

Indexed as

Cardiovascular DiseasesHIV InfectionsAfrica, NorthernAgedFemaleHumansLesothoNamibiaPrevalenceSenegalSouth AfricaCardiovascular diseaseDemographic and Health SurveyDiabetesHIVHypertension

Identifiers

PMID34118912
PMCPMC8196536
OpenAlexW3167486863

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.