Evidence map›Paper›PMID 34118786›Full record

SynthesisHeart & lung : the journal of critical care

Mortality of right ventricular dysfunction in patients with acute respiratory distress syndrome subjected to lung protective ventilation: A systematic review and meta-analysis.

Daoran Dong, Yuan Zong, Zhuo Li, Yan Wang, Chengqiao Jing

2 registry-linked trialsOpen access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05414110 unknown statusnot on this map

Effect of Airway Pressure Release Ventilation(APRV) on Right Ventricular Function Assessed by Transthoracic Echocardiography

TypeobservationalSponsorUnion Hospital, Tongji Medical College, Huazhong University of Science and TechnologyRan2022 to 2024Enrolled50ConditionsVentilation Therapy, Complications, Right Ventricular Function, ARDS
NCT05922631 nacompletednot on this map

Effect of Airway Pressure Release Ventilation vs. Low Tidal Volume Ventilation on Right Heart Function in Acute Respiratory Distress Syndrome Patients: a Single-center Randomized Controlled Study

TypeinterventionalSponsorXiaoJing Zou,MDRan2023 to 2025Enrolled60ConditionsRight Heart Failure, Mechanical Ventilation, Acute Respiratory Distress SyndromeArmsAirway pressure release ventilation, low tidal volume
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daoran DongDepartment of ICU, Shaanxi Provincial People's Hospital, Xi'an, China. Electronic address: sxsrmyyicu11@outlook.com.
Yuan ZongDepartment of ICU, Shaanxi Provincial People's Hospital, Xi'an, China.
Zhuo LiDepartment of ICU, Shaanxi Provincial People's Hospital, Xi'an, China.
Yan WangDepartment of ICU, Shaanxi Provincial People's Hospital, Xi'an, China.
Chengqiao JingDepartment of ICU, Shaanxi Provincial People's Hospital, Xi'an, China.
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of right ventricular dysfunction(RVD) on the prognosis of acute respiratory distress syndrome(ARDS) patients is controversial.

objectivesThe objectives of this systematic review and meta-analysis was to investigate whether RVD or pulmonary vascular dysfunction are associated with increased mortality in patients with ARDS.

methodsWe searched Pubmed, Embase, Cochrane Library, Wanfang Data, CNKI, and the WHO Clinical Trial Registry for studies of RVD or pulmonary vascular dysfunction in patients with ARDS.

resultsThe presence of RVD or pulmonary vascular dysfunction in patients with ARDS was associated with an increase in mortality (OR = 1.68, 95% CI = 1.21-2.32, P = 0.069, I

conclusionThe prognosis of patients with ARDS and RVD or pulmonary vascular dysfunction is worse than that of ARDS patients without RVD or pulmonary vascular dysfunction.

Indexed as

Respiratory Distress SyndromeVentricular Dysfunction, RightHumansLungPrognosisRespiration, ArtificialAcute cor pulmonaleAcute respiratory distress syndromePrognosisPulmonary vascular dysfunctionRight ventricular dysfunction

Identifiers

PMID34118786
PMCPMC9754927
OpenAlexW3170090290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.