Evidence map›Paper›PMID 34118500›Full record

SynthesisBrain and cognition2021

Lesion loci of impaired affective prosody: A systematic review of evidence from stroke.

Alexandra Zezinka Durfee, Shannon M Sheppard, Margaret L Blake, Argye E Hillis

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Brain and cognition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. The Company Prosodic Deficits Keep Following Right Hemisphere Stroke: A Systematic Review.Journal of the International Neuropsychological Society : JINS · 2022
    Pooled it
  3. Multi-modal lesion mapping of expressive aprosodia.Cortex; a journal devoted to the study of the nervous system and behavior · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alexandra Zezinka DurfeeDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. Electronic address: adurfee1@jhmi.edu.
Shannon M SheppardDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Communication Sciences and Disorders, Chapman University Crean College of Health and Behavioral Sciences, Irvine, CA 92618, United States.
Margaret L BlakeDepartment of Communication Sciences and Disorders, University of Houston College of Liberal Arts and Social Sciences, Houston, TX 77204, United States.
Argye E HillisDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Cognitive Science, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218, United States.
Johns Hopkins Medicine · USJohns Hopkins University · USUniversity of Houston · US

Funding

Neural Basis of Lexical Deficits in Hyperacute StrokeR01DC005375 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Argye E. Hillis · 2002 to 2026
$11.8M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
NIDCD NIH HHS R01 DC005375NIDCD NIH HHS R01 DC015466
6 · The paper itself

Abstract

Affective prosody, or the changes in rate, rhythm, pitch, and loudness that convey emotion, has long been implicated as a function of the right hemisphere (RH), yet there is a dearth of literature identifying the specific neural regions associated with its processing. The current systematic review aimed to evaluate the evidence on affective prosody localization in the RH. One hundred and ninety articles from 1970 to February 2020 investigating affective prosody comprehension and production in patients with focal brain damage were identified via database searches. Eleven articles met inclusion criteria, passed quality reviews, and were analyzed for affective prosody localization. Acute, subacute, and chronic lesions demonstrated similar profile characteristics. Localized right antero-superior (i.e., dorsal stream) regions contributed to affective prosody production impairments, whereas damage to more postero-lateral (i.e., ventral stream) regions resulted in affective prosody comprehension deficits. This review provides support that distinct RH regions are vital for affective prosody comprehension and production, aligning with literature reporting RH activation for affective prosody processing in healthy adults as well. The impact of study design on resulting interpretations is discussed.

Indexed as

Speech PerceptionStrokeAdultComprehensionEmotionsHumansBrain mappingCommunicationEmotionProsodyStroke

Identifiers

PMID34118500
PMCPMC8324538
OpenAlexW3170904343

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.