Evidence map›Paper›PMID 34118307›Full record

ReviewNeuroscience letters2021

Guillain Barrè syndrome and myelitis associated with SARS-CoV-2 infection.

Isabella Canavero, Sabrina Ravaglia, Francesca Valentino, Giuseppe Micieli

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Isabella CanaveroCurrent affiliation: Cerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; Emergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy. Electronic address: isabella.canavero@istituto-besta.it.
Sabrina RavagliaEmergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy.
Francesca ValentinoEmergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy.
Giuseppe MicieliEmergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy.
Fondazione Istituto Neurologico Nazionale Casimiro Mondino · ITFondazione IRCCS Istituto Neurologico Carlo Besta · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite a likely underestimation due to the many obstacles of the highly infectious, intensive care setting, increasing clinical reports about COVID-19 patients developing acute paralysis for polyradiculoneuritis or myelitis determine additional impact on the disease course and outcome. Different pathogenic mechanisms have been postulated basing on clinical, laboratory and neuroimaging features, and response to treatments. Here we provide an overview with insights built on the available reports. Besides direct viral pathogenicity, a crucial role seems to be represented by immune-mediated mechanisms, supporting and further characterizing the already hypothesized neurotropic potential of SARS-CoV-2 and implying specific treatments. Proper clinical and instrumental depiction of symptomatic cases, as well as screening for their early recognition is advocated.

Indexed as

COVID-19Guillain-Barre SyndromeHumansMyelitisSARS-CoV-2COVID-19Guillain Barrè syndromeImmune-mediated demyelinationMyelitisSARS-CoV-2

Identifiers

PMID34118307
PMCPMC8189748
OpenAlexW3168609008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.