Evidence map›Paper›PMID 34118133›Full record

ArticleLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society2021

Utility of Preoperative Computed Tomography-Based Body Metrics in Relation to Postoperative Complications in Pediatric Liver Transplantation Recipients.

Martijn V Verhagen, Stef Levolger, Jan Binne Hulshoff, Maureen J M Werner, Hubert P J van der Doef, Alain R Viddeleer, Ruben H de Kleine, Robbert J de Haas

Open access · hybridAbstract read
In one paragraph

Article in Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Martijn V VerhagenDepartment of RadiologyUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.ORCID 0000-0001-9804-5781
Stef LevolgerDepartment of RadiologyUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.
Jan Binne HulshoffDepartment of RadiologyUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.
Maureen J M WernerDepartment of Hepatobiliary Surgery and Liver TransplantationUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.ORCID 0000-0002-5542-0286
Hubert P J van der DoefDepartment of Pediatric GastroenterologyUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.
Alain R ViddeleerDepartment of RadiologyUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.
Ruben H de KleineDepartment of Hepatobiliary Surgery and Liver TransplantationUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.
Robbert J de HaasDepartment of RadiologyUniversity Medical Center GroningenUniversity of GroningenGroningenthe Netherlands.
University Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computed tomography (CT)-derived body metrics such as skeletal muscle index (SMI), psoas muscle index (PMI), and subcutaneous fat area index (ScFI) are measurable components of sarcopenia, frailty, and nutrition. While these body metrics are advocated in adults for predicting postoperative outcomes after liver transplantation (LT), little is known about their value in pediatric populations. This study assessed the relation between preoperative CT-based body metrics and postoperative short-term outcomes in pediatric LT recipients. Patients aged 0-18 years who underwent a primary LT were retrospectively included (n = 101; median age 0.5 years; range 0.2-17.1). SMI, PMI, and ScFI were derived from preoperative axial CT slices. Postoperative outcomes and complications within 90 days were correlated with the CT-based body metrics. To classify postoperative infections, the Clavien-Dindo (CD) classification was used. Subgroup analyses were performed for age groups (<1, 1-10, and >10 years old). An optimal threshold for test performance was defined using Youden's J-statistic and receiver operating characteristic curve as appropriate. ScFI was significantly (P = 0.001) correlated with moderate to severe postoperative infections (CD grade 3-5) in children aged <1 year, with the optimal ScFI threshold being ≤27.1 cm

Indexed as

Liver TransplantationSarcopeniaAdolescentAdultAgedChildChild, PreschoolHumansInfantInfant, NewbornPostoperative ComplicationsPsoas MusclesRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID34118133
PMCPMC9291866
OpenAlexW3170354318

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.