Evidence map›Paper›PMID 34118030›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Synthesis and Characterization of Mitochondria-Targeted Triphenylphosphonium Bolaamphiphiles.

Francesca Ceccacci, Simona Sennato, Edoardo Rossi, Raffaele Proroga, Stefano Sarti, Marco Diociaiuti, Stefano Casciardi, Valentina Mussi, Alessia Ciogli, Federico Bordi and 2 more

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Efficacy of phosphonium amphiphilic salts against Acanthamoeba genotype T4.International journal for parasitology. Drugs and drug resistance · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesca CeccacciCNR-ISB, Sede Secondaria di Roma-Meccanismi di Reazione c/o Department of Chemistry, Sapienza University, Roma, Italy.
Simona SennatoCNR-ISC-UOS Sapienza c/o Physics Department, Sapienza University, Roma, Italy.
Edoardo RossiDepartment of Chemistry, Sapienza University, Roma, Italy.
Raffaele ProrogaDepartment of Chemistry, Sapienza University, Roma, Italy.
Stefano SartiPhysics Department, Sapienza University, Roma, Italy.
Marco DiociaiutiCentro Nazionale Malattie Rare, Istituto Superiore di Sanità, Roma, Italy.
Stefano CasciardiDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, National Institute for Insurance against Accidents at Work (INAIL), Rome, Italy.
Valentina MussiCNR-IMM Institute of Microelectronics and Microsystems, Roma, Italy.
Alessia CiogliDepartment of Chemistry and Technology of Drug, Sapienza University, Roma, Italy.
Federico BordiPhysics Department, Sapienza University, Roma, Italy.
Giovanna ManciniCNR-ISB, Monterotondo, Italy.
Cecilia BombelliCNR-ISB, Sede Secondaria di Roma-Meccanismi di Reazione c/o Department of Chemistry, Sapienza University, Roma, Italy. cecilia.bombelli@cnr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this chapter we describe: (1) the procedure for the synthesis of four single chain bolaamphiphiles, displaying chains of 12, 16, 20 and 30 methylene units and triphenylphosphonium moieties as headgroups (TPP1-TPP4); (2) the methods used to characterize TPP1-TPP4 spontaneous aggregation in aqueous solution. We illustrate the determination of Krafft point and cac by conductivity measurements and the procedures used to investigate dimensions, morphology, and stability by dynamic and dielectrophoretic laser light scattering, dialysis, transmission electron microscopy, and Raman spectroscopy measurements.

Indexed as

Dynamic Light ScatteringFuransMicroscopy, Electron, TransmissionMitochondriaMolecular StructureOrganophosphorus CompoundsPyridonesSpectrum Analysis, RamanWaterbolaamphiphileFuransOrganophosphorus CompoundsPyridonesWaterEquilibrium systemsKinetic trapsKolbe electrolysisThermomorphic electrolytic solutionTriphenylphosphonium bolaamphiphilesU-shaped/extended conformation

Identifiers

PMID34118030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.