ArticleEJNMMI physics2021
Design and system evaluation of a dual-panel portable PET (DP-PET).
Article in EJNMMI physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Impact of depth-of-interaction and spatially-variant point-spread-function model on the performance of ultra-high resolution brain PET.Physics in medicine and biology · 2026Article
- Deep unrolled regularization for limited-angle dual-panel positron emission mammography.Physical and engineering sciences in medicine · 2026Article
- Image reconstruction and elongation artifact reduction for a dual-panel dedicated prostate PET scanner.Medical physics · 2026Article
- Design of a Mobile and Electromagnetic Emissions-Compliant Brain Positron Emission Tomography (PET) Scanner.Sensors (Basel, Switzerland) · 2025Article
- Performance evaluation of a medium axial field-of-view sparse PET system based on flat panels of monolithic LYSO detectors: a simulation study.EJNMMI physics · 2025Article
- Design and proof of concept of a double-panel TOF-PET system.EJNMMI physics · 2024Article
- Dynamic Human Brain Imaging with a Portable PET Camera: Comparison to a Standard Scanner.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- Crystal scatter effects in a large-area dual-panel Positron Emission Mammography system.PloS one · 2024Article
- The quest for multifunctional and dedicated PET instrumentation with irregular geometries.Annals of nuclear medicine · 2024Review
- Cross-Attention for Improved Motion Correction in Brain PET.Machine learning in clinical neuroimaging : 6th international workshop, MLCN 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8, 2023, proceedings. MLCN (Workshop) (6th : 2023 : Vancouver, B.C.) · 2023Article
- Brain imaging of sequential acquisition using a flexible PET scanner and 3-T MRI: quantitative and qualitative assessment.Annals of nuclear medicine · 2023Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIntegrated whole-body PET/MR technology continues to mature and is now extensively used in clinical settings. However, due to the special design architecture, integrated whole-body PET/MR comes with a few inherent limitations. Firstly, whole-body PET/MR lacks sensitivity and resolution for focused organs. Secondly, broader clinical access of integrated PET/MR has been significantly restricted due to its prohibitively high cost. The MR-compatible PET insert is an independent and removable PET scanner which can be placed within an MRI bore. However, the mobility and configurability of all existing MR-compatible PET insert prototypes remain limited.
methodsAn MR-compatible portable PET insert prototype, dual-panel portable PET (DP-PET), has been developed for simultaneous PET/MR imaging. Using SiPM, digital readout electronics, novel carbon fiber shielding, phase-change cooling, and MRI compatible battery power, DP-PET was designed to achieve high-sensitivity and high-resolution with compatibility with a clinical 3-T MRI scanner. A GPU-based reconstruction method with resolution modeling (RM) has been developed for the DP-PET reconstruction. We evaluated the system performance on PET resolution, sensitivity, image quality, and the PET/MR interference.
resultsThe initial results reveal that the DP-PET prototype worked as expected in the MRI bore and caused minimal compromise to the MRI image quality. The PET performance was measured to show a spatial resolution ≤ 2.5 mm (parallel to the detector panels), maximum sensitivity = 3.6% at the center of FOV, and energy resolution = 12.43%. MR pulsing introduces less than 2% variation to the PET performance measurement results.
conclusionsWe developed a MR-compatible PET insert prototype and performed several studies to begin to characterize the performance of the proposed DP-PET. The results showed that the proposed DP-PET performed well in the MRI bore and would cause little influence on the MRI images. The Derenzo phantom test showed that the proposed reconstruction method could obtain high-quality images using DP-PET.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.