ArticleJournal of veterinary internal medicine2021
Clinical features, diagnosis, and survival analysis of dogs with glioma.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 68 citations in OpenAlex.
- Epidemiological analysis of brain tumours in dogs in Australia between 1994 and 2024.Scientific reports · 2026Article
- Unusually slow progression of a high-grade intramedullary oligodendroglioma in a dog: serial magnetic resonance imaging findings and clinical course over two years.Journal of veterinary internal medicine · 2026Article
- Magnetic resonance imaging of primary central nervous system neoplasms of dogs and cats: Basic concepts for diagnostic pathologists.Veterinary pathology · 2026Review
- Immunohistochemical characterization of neural stem cells in brains of adult brachycephalic dogs in comparison with canine oligodendroglioma cells.The Journal of veterinary medical science · 2026Article
- Optic Chiasm and Bilateral Optic Nerve Oligodendroglioma in A 29-Month-Old German Shepherd.Veterinary ophthalmology · 2026Article
- French Bulldog Diagnosed With a Suspected Brain Tumor Shortly After Treatment for Spinal Arachnoid Diverticulum.Case reports in veterinary medicine · 2026Article
- Radiomics and comparative neuroimaging of canine gliomas and human glioblastomas: a step toward precision medicine.Frontiers in veterinary science · 2026Article
- A comparative evaluation of canine meningioma supporting the canine patient as a naturally occurring animal model for human meningioma: a report from the NCI Comparative Brain Tumor Consortium (CBTC) meningioma pathology board.Veterinary oncology (London, England) · 2026Article
- Systemic mRNA vaccines elicit rapid immune activation in canine brain tumors.Journal for immunotherapy of cancer · 2025Article
- Adapting Laser Interstitial Thermal Therapy for the Treatment of Naturally Occurring Intracranial Tumors in Dogs.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Article
- Possible involvement of cerebrospinal fluid drop metastasis in the survival of French bulldogs after radiotherapy for presumed glial brain tumors.Open veterinary journal · 2025Article
- Differential gene expression analysis in French bulldog high grade oligodendroglioma: breed-associated differences in tumor and tumor microenvironment gene expression.Companion animal health and genetics · 2025Article
- Telovelar Approach for the Surgical Resection of a Caudal Fossa Glioma in a Toy Poodle.Animals : an open access journal from MDPI · 2025Article
- Immunotherapy yields breed-specific worst survival outcomes among three investigated therapies in French bulldogs with high-grade glioma.Frontiers in veterinary science · 2025Article
- Breed-Associated Differences in Differential Gene Expression Following Immunotherapy-Based Treatment of Canine High-Grade Glioma.Animals : an open access journal from MDPI · 2024Article
- Bringing the Genomic Revolution to Comparative Oncology: Human and Dog Cancers.Annual review of biomedical data science · 2024Review
- Immunohistochemical Expression of PTEN in Canine Gliomas.Animals : an open access journal from MDPI · 2024Article
- Canine glioma in the first year of life: 5 cases.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Article
- Common Neurologic Diseases in Geriatric Dogs.Animals : an open access journal from MDPI · 2024Review
- An Illustrated Scoping Review of the Magnetic Resonance Imaging Characteristics of Canine and Feline Brain Tumors.Animals : an open access journal from MDPI · 2024Article
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Authors and funding
16 authors at 9 institutions in 6 countries.
Funding
Abstract
backgroundGliomas in dogs remain poorly understood.
objectivesTo characterize the clinicopathologic findings, diagnostic imaging features and survival of a large sample of dogs with glioma using the Comparative Brain Tumor Consortium diagnostic classification. ANIMALS: Ninety-one dogs with histopathological diagnosis of glioma.
methodsMulticentric retrospective case series. Signalment, clinicopathologic findings, diagnostic imaging characteristics, treatment, and outcome were used. Tumors were reclassified according to the new canine glioma diagnostic scheme.
resultsNo associations were found between clinicopathologic findings or survival and tumor type or grade. However, definitive treatments provided significantly (P = .03) improved median survival time (84 days; 95% confidence interval [CI], 45-190) compared to palliative treatment (26 days; 95% CI, 11-54). On magnetic resonance imaging (MRI), oligodendrogliomas were associated with smooth margins and T1-weighted hypointensity compared to astrocytomas (odds ratio [OR], 42.5; 95% CI, 2.42-744.97; P = .04; OR, 45.5; 95% CI, 5.78-333.33; P < .001, respectively) and undefined gliomas (OR, 84; 95% CI, 3.43-999.99; P = .02; OR, 32.3; 95% CI, 2.51-500.00; P = .008, respectively) and were more commonly in contact with the ventricles than astrocytomas (OR, 7.47; 95% CI, 1.03-53.95; P = .049). Tumor spread to neighboring brain structures was associated with high-grade glioma (OR, 6.02; 95% CI, 1.06-34.48; P = .04). CONCLUSIONS AND CLINICAL IMPORTANCE: Dogs with gliomas have poor outcomes, but risk factors identified in survival analysis inform prognosis and the newly identified MRI characteristics could refine diagnosis of tumor type and grade.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.