ArticleCancer medicine2021
Preoperative histogram parameters of dynamic contrast-enhanced MRI as a potential imaging biomarker for assessing the expression of Ki-67 in prostate cancer.
Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Multiparametric MRI-based radiomics model integrating tumor lesion and periprostatic adipose tissue for predicting bone metastasis in prostate cancer.Frontiers in oncology · 2026Article
- Deep learning-based radiomic nomograms for predicting Ki67 expression in prostate cancer.BMC cancer · 2023Article
- Ki67 and the apparent diffusion coefficient in postoperative prostate cancer with endocrine therapy.Frontiers in surgery · 2023Article
- Association Between DCE-MRI Perfusion Histogram Parameters and EGFR and VEGF Expressions in Different Lauren Classifications of Advanced Gastric Cancer.Pathology oncology research : POR · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeTo investigate whether preoperative histogram parameters of dynamic contrast-enhanced MRI (DCE-MRI) can assess the expression of Ki-67 in prostate cancer (PCa). MATERIALS AND
methodsA consecutive series of 76 patients with pathology-proven PCa who underwent routine DCE-MRI scans were retrospectively recruited. Quantitative parameters including the volume transfer constant (K
resultsEighty-eight PCa lesions were enrolled in this study, including 31 lesions with high Ki-67 expression and 57 lesions with low Ki-67 expression. The median, mean, 75th percentile, and 90th percentile derived from K
conclusionThe histogram of DCE-MRI quantitative parameters is correlated with Ki-67 expression, which has the potential to noninvasively assess the expression of Ki-67 with patients of PCa.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.