Trial reportDysphagia2022
Swallowing Exercise During Head and Neck Cancer Treatment: Results of a Randomized Trial.
Trial report in Dysphagia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Impact of Oncological Treatment on Quality of Life in Patients with Head and Neck Malignancies: A Systematic Literature Review (2020-2025).Current oncology (Toronto, Ont.) · 2025Pooled it
- Guidelines for the Treatment of Laryngeal Cancer from the Korean Society of Head and Neck Surgery.Clinical and experimental otorhinolaryngology · 2025Guideline
- Effectiveness of Home-Based Telerehabilitation Interventions for Dysphagia in Patients With Head and Neck Cancer: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Exercise-based rehabilitation on functionality and quality of life in head and neck cancer survivors. A systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Trial
- Effect tongue pressure feedback training with enabling education on swallowing and depression in head and neck tumor patients.World journal of psychiatry · 2025Trial
- Preventing radiation-induced dysphagia and trismus in head and neck cancer-A randomized controlled trial.Head & neck · 2025Trial
- Prophylactic Swallowing Exercises in Patients with Laryngeal Cancer Who Underwent Total Laryngectomy-A Randomized Trial.Current oncology (Toronto, Ont.) · 2024Trial
- Effect of Oral Somatosensory Training on Oral Somatosensory Dysfunction in Head and Neck Cancer Survivors.Asian Pacific journal of cancer prevention : APJCP · 2024Trial
- A randomized controlled study evaluating the head-lift exercise in head and neck cancer patients with radiation-induced dysphagia: effect on swallowing function and health-related quality of life over 12 months.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Trial
- Article
- Evaluation of Swallowing Function and Aspiration in Newly Diagnosed Head and Neck Cancer Patients.Dysphagia · 2026Article
- Effectiveness of Gamified Swallowing Exercises in Adults With Dysphagia: Systematic Review and Meta-Analysis of Randomized Controlled Trials.JMIR serious games · 2026Review
- Effectiveness of gamified swallowing exercise in adults with dysphagia: protocol for a systematic review and meta-analysis.Systematic reviews · 2026Article
- Precision rehabilitation for swallowing dysfunction after radiotherapy in head and neck cancer: current evidence, key controversies, and future perspectives.Frontiers in oncology · 2026Review
- Application of the Plan-Do-Check-Act Cycle in Reducing the Incidence of Dysphagia in Oral Cancer Patients After Radical Surgery.Journal of multidisciplinary healthcare · 2026Article
- Effect of Nurse-Led Swallowing Rehabilitation on Swallowing Function, Quality of Life, and Adherence in Patients with Oral Cancer: A Single Center Randomized Controlled Trial.Patient preference and adherence · 2026Article
- A barrier-forming gel for oral mucositis in head and neck cancers patients undergoing radiotherapy: randomized, controlled, multicenter trial.EClinicalMedicine · 2025Article
- Predictive Power of Pharyngolaryngeal Secretion Accumulations for Penetration and Aspiration in Head and Neck Cancer Patients.Dysphagia · 2025Article
- The Rationale and Explanation for Rehabilitation Interventions in the Management of Treatment-Induced Trismus in People with Head and Neck Cancer: A Scoping Review of Randomized Controlled Trials.Medicina (Kaunas, Lithuania) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis and treatment of head and neck cancer (HNC) can have substantial impact on swallowing function, nutritional balance, physical function and quality of life (QoL). Early initiated swallowing exercises are hypothesized to improve swallowing function in HNC patients. The aim was to investigate the effects of swallowing exercises and progressive resistance training (PRT) during radiotherapy on swallowing function, physical function and QoL in patients with pharynx-, larynx-, oral cavity cancer or unknown primary compared to usual care. In a multi-centre RCT participants were assigned to (a) twice-weekly PRT and daily swallowing exercises throughout treatment or (b) usual care. Outcomes were measured at end of treatment and 2, 6 and 12 months after. Primary outcome was penetration aspiration score (PAS). Data were analysed on an "intention-to-treat" basis by GEE logistic regression model, linear mixed effects model and cox regression. Of 371 invited HNC patients, 240 (65%) enrolled. Five participants were excluded. At 12 months follow-up, 59 (25%) participants were lost. Analyses showed significant effect on mouth opening, QoL, depression and anxiety at 12 months when comparing intervention to non-active controls. The trial found no effect on swallowing safety in HNC undergoing radiotherapy, but several positive effects were found on secondary outcomes when comparing to non-active controls. The intervention period may have been too short, and the real difference between groups is too small. Nevertheless, the need to identify long-lasting intervention to slow down or avoid functional deteriorations is ever more crucial as the surviving HNC population is growing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.