ArticleScientific reports2021
Selective control of the contact and transport between droplet pairs by electrowetting-on-dielectric for droplet-array sandwiching technology.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Application of Droplet-Array Sandwiching Technology to Click Reactions for High-Throughput Screening.Micromachines · 2025Article
- Resonant oscillation of droplets under an alternating electric field to enhance solute diffusion.Scientific reports · 2024Article
- Single-Cell RNA Sequencing in Organ and Cell Transplantation.Biosensors · 2024Review
- Enhancement of solute diffusion in microdroplets using microrotors under rotational magnetic field.Scientific reports · 2023Article
- Threshold magnetic field as a universal criterion for the selective transport of magnetized particles in microdroplets.Scientific reports · 2023Article
- Bioinspired magnetic cilia: from materials to applications.Microsystems & nanoengineering · 2023Review
- Article
- Emergence of uniform linearly-arranged micro-droplets entrapping DNA and living cells through water/water phase-separation.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methodological advances in on-chip technology enable high-throughput drug screening, such as droplet-array sandwiching technology. Droplet-array sandwiching technology involves upper and lower substrates with a droplet-array designed for a one-step process. This technology is, however, limited to batch manipulation of the droplet-array. Here, we propose a method for selective control of individual droplets, which allows different conditions for individual droplet pairs. Electrowetting-on-dielectric (EWOD) technology is introduced to control the height of the droplets so that the contact between droplet-pairs can be individually controlled. Circular patterns 4 mm in diameter composed of electrodes for EWOD and hydrophilic-hydrophobic patterns for droplet formation 4 μl in volume were developed. We demonstrate the selective control of the droplet height by EWOD for an applied voltage up to 160 V and selective control of the contact and transport of substances. Presented results will provide useful method for advanced drug screening, including cell-based screening.
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Registered trials
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