ArticleNature communications2021
Delineation of an insula-BNST circuit engaged by struggling behavior that regulates avoidance in mice.
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Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
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Who cites it
45 citing papers in PubMed.
- Alcohol abstinence precipitates alcohol seeking and aversion-resistant intake in association with increased BNST activity.Molecular psychiatry · 2026Article
- Comparative insights into insula structure and function.Nature neuroscience · 2026Review
- Dissociable control of depression and visceral pain by the pICNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- HERO: A hierarchy-aware analysis pipeline for reducing and refining whole-brain atlas-mapped cellular datasets.bioRxiv : the preprint server for biology · 2026Article
- From Efference Copy to Emotional State: Insular Cortex Somatostatin Neurons Buffer Adaptive Responses to Physical Stress.Biological psychiatry global open science · 2026Article
- Insular Somatostatin Interneurons Are Targeted by Motor Cortex Efferents and Modulate Affective States.Biological psychiatry global open science · 2026Article
- Dorsal striatal circuit mechanisms contributing to astrocyte modulation of alcohol-related behaviors.bioRxiv : the preprint server for biology · 2026Article
- The S1-insula Circuit Differentially Modulates Alcohol Drinking and Aversive Behavior in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Chronic Stress Alters Dorsal Bed Nucleus of Stria Terminalis Synaptic Neurotransmission in a Dravet Syndrome Mouse Model.bioRxiv : the preprint server for biology · 2026Article
- Association of stress-sensitive mid-insula activity with alcohol drinking and negative affect-like behavior during abstinence in mice.Neuropharmacology · 2026Article
- Sex-specific relationships between stress coping and avoidance behavior in adult mice.Biology of sex differences · 2026Article
- Bed nucleus of the stria terminalis connectivity during food cue and taste processing under stress.Nature communications · 2026Article
- Sex-specific relationships between stress coping and avoidance behavior.bioRxiv : the preprint server for biology · 2026Article
- The bed nucleus of the stria terminalis as a neuromodulatory target for refractory epilepsy.Frontiers in network physiology · 2026Review
- Epigenetic manipulation of anterior insular cortex alters neural signals and cognitive control.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Fiber Photometry Analysis of Spontaneous Dopamine Signals: TheACS chemical neuroscience · 2025Article
- Sexually Dimorphic Cellular Architecture and Neural Circuity of ovBNST Proenkephalin Neurons.Neuroscience bulletin · 2025Article
- Acute stress causes sex-specific changes to ventral subiculum synapses, circuitry, and anxiety-like behavior.Nature communications · 2025Article
- Opposite-sex pairing alters social-induced GCaMP and dopamine activity in the insula of male prairie voles.Annals of the New York Academy of Sciences · 2025Article
- Early life psychosocial stress increases binge-like ethanol consumption and CSF1R inhibition prevents stress-induced alterations in microglia and brain macrophage population density.Brain, behavior, & immunity - health · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Joseph R LuchsingerVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0001-8577-2947
Tracy L FetterlyVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA.
Kellie M WillifordVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0002-7405-6459
Gregory J SalimandoVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA.
Marie A DoyleVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA.
Jose MaldonadoVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA.
Richard B SimerlyVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA. richard.simerly@vanderbilt.edu.ORCID 0000-0001-5840-0152
Danny G WinderVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA. danny.winder@vanderbilt.edu.ORCID 0000-0002-6185-4769
Samuel W CentanniVanderbilt Center for Addiction Research, Vanderbilt University School of Medicine, Nashville, TN, USA. samuel.centanni@vanderbilt.edu.ORCID 0000-0002-3941-7677
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3MOverall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3MProgram in NeurogenomicsT32MH065215 · NIMH · VANDERBILT UNIVERSITY · PI ROGER J COLBRAN · 2002 to 2026
$6.4MMedical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8MSex Dependent Recruitment of PKCdelta Neurons by Stress: Administrative Supplement for Noradrenergic Regulation in the BNSTR01DA042475 · NIDA · VANDERBILT UNIVERSITY · PI WINDER, DANNY G. · 2016 to 2025
$4.0MAlcohol action on extended amygdala glutamate synapsesR37AA019455 · NIAAA · VANDERBILT UNIVERSITY · PI WINDER, DANNY G. · 2015 to 2024
$3.9MLeptin and Developmental Programming of Hypothalamic Autonomic OutflowR01DK106476 · NIDDK · VANDERBILT UNIVERSITY · PI SIMERLY, RICHARD B · 2016 to 2024
$3.7MInsular Cortex-BNST neural circuit regulation of chronic alcohol abstinence-induced negative affectK99AA027774 · NIAAA · VANDERBILT UNIVERSITY · PI CENTANNI, SAMUEL · 2020 to 2021
$300kIdentification and modulation of insula to BNST circuit specific afferents in ethanol abstinenceF30AA027126 · NIAAA · VANDERBILT UNIVERSITY · PI LUCHSINGER, JOSEPH RICHARD · 2019 to 2021
$111kBNST PKCdelta Roles in Affective BehaviorF99NS120599 · NINDS · VANDERBILT UNIVERSITY · PI WILLIFORD, KELLIE M · 2020 to 2021
$63kNIAAA NIH HHS F30 AA027126NIAAA NIH HHS K99 AA027774NIAAA NIH HHS R37 AA019455NICHD NIH HHS P50 HD103537NIDA NIH HHS R01 DA042475NIDDK NIH HHS R01 DK106476NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284NIMH NIH HHS T32 MH065215NINDS NIH HHS F99 NS120599
Abstract
Active responses to stressors involve motor planning, execution, and feedback. Here we identify an insular cortex to BNST (insula
Indexed as
Avoidance LearningBehavior, AnimalAmygdalaAnimalsBrainCerebral CortexFemaleMiceMice, Inbred C57BLNeuronsSomatosensory Cortex
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.