Evidence map›Paper›PMID 34117047›Full record

ArticleBMJ open2021

Diet and physical activity in pregnancy to prevent gestational diabetes: a protocol for an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation.

Dyuti Coomar, Jonathan M Hazlehurst, Frances Austin, Charlie Foster, Graham A Hitman, Nicola Heslehurst, Stamatina Iliodromiti, Ana Pilar Betran, Ngawai Moss, Lucilla Poston and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 3 countries.

Dyuti CoomarInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Jonathan M HazlehurstWHO Collaborating Centre for Global Women's Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK j.m.hazlehurst@bham.ac.uk.ORCID 0000-0003-1036-103X
Frances AustinMaternity Dietetic Service, Women's Health Division, Barts Health NHS Trust, Antenatal Clinic, Royal London Hospital and Newham University Hospital, London, UK.
Charlie FosterCentre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK.
Graham A HitmanCentre for Genomic Medicine and Child Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nicola HeslehurstPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Stamatina IliodromitiCentre for Women's Health, Institute of Population Health Sciences, Queen Mary University of London, London, UK.
Ana Pilar BetranUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, WHO, Geneva, Switzerland.
Ngawai MossKatie's Team Patient and Public Involvement Advisory Group, Queen Mary University of London, London, UK.
Lucilla PostonDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
Krishnarajah NirantharakumarInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Tracy RobertsHealth Economics Unit, University of Birmingham, Birmingham, UK.
Sharon A SimpsonMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
Helena J TeedeMonash Centre for Health Research and Implementation, School of Public Health, Monash University, Melbourne, Victoria, Australia.
Richard RileyCentre for Prognosis Research, School of Medicine, Keele University, Keele, UK.
John AlloteyInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Shakila ThangaratinamWHO Collaborating Centre for Global Women's Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
International Weight Management in Pregnancy (i-WIP) Collaborative Group
Queen Mary University of London · GBUniversity of Birmingham · GBBarts Health NHS Trust · GBBirmingham Women’s and Children’s NHS Foundation Trust · GBKeele University · GBKing's College London · GBMonash University · AUMRC/CSO Social and Public Health Sciences Unit · GBNewcastle University · GBUniversity of Bristol · GBWorld Health Organization · CH

Funding

Chief Scientist Office SPHSU14Chief Scientist Office SPHSU16Medical Research Council MC_PC_13027Medical Research Council MC_UU_00022/1Medical Research Council MC_UU_12017/14Medical Research Council MR/K02325X/1World Health Organization 001
6 · The paper itself

Abstract

introductionMothers with gestational diabetes mellitus (GDM) are at increased risk of pregnancy-related complications and developing type 2 diabetes after delivery. Diet and physical activity-based interventions may prevent GDM, but variations in populations, interventions and outcomes in primary trials have limited the translation of available evidence into practice. We plan to undertake an individual participant data (IPD) meta-analysis of randomised trials to assess the differential effects and cost-effectiveness of diet and physical activity-based interventions in preventing GDM and its complications.

methodsThe International Weight Management in Pregnancy Collaborative Network database is a living repository of IPD from randomised trials on diet and physical activity in pregnancy identified through a systematic literature search. We shall update our existing search on MEDLINE, Embase, BIOSIS, LILACS, Pascal, Science Citation Index, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews of Effects and Health Technology Assessment Database without language restriction to identify relevant trials until March 2021. Primary researchers will be invited to join the Network and share their IPD. Trials including women with GDM at baseline will be excluded. We shall perform a one and two stage random-effect meta-analysis for each intervention type (all interventions, diet-based, physical activity-based and mixed approach) to obtain summary intervention effects on GDM with 95% CIs and summary treatment-covariate interactions. Heterogeneity will be summarised using I ETHICS AND DISSEMINATION: Ethics approval is not required. The study is registered on the International Prospective Register of Systematic Reviews (CRD42020212884). Results will be submitted for publication in peer-reviewed journals.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2Cost-Benefit AnalysisDietExerciseFemaleHumansMeta-Analysis as TopicPregnancySystematic Reviews as Topicdiabetes & endocrinologydiabetes in pregnancymaternal medicinenutrition & dietetics

Identifiers

PMID34117047
PMCPMC8202105
OpenAlexW3152621699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.