Evidence map›Paper›PMID 34116864›Full record

ReviewTrends in genetics : TIG2021

A molecular toolkit for superorganisms.

Bogdan Sieriebriennikov, Danny Reinberg, Claude Desplan

Open access · greenAbstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Genome Evolution in Social Insects.Genome biology and evolution · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Hi-C sequencing unravels dynamic three-dimensional chromatin interactions in muntjac lineage: insights from chromosome fusions in Fea's muntjac genome.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023
    Article
  6. Neuromodulators and neuroepigenetics of social behavior in ants.Annals of the New York Academy of Sciences · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bogdan SieriebriennikovDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA; Department of Biology, New York University, New York, NY, USA.
Danny ReinbergDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY, USA. Electronic address: danny.reinberg@nyulangone.org.
Claude DesplanDepartment of Biology, New York University, New York, NY, USA. Electronic address: cd38@nyu.edu.
New York University · USHoward Hughes Medical Institute · US

Funding

Aging and rejuvenation: An ant model to study the regulation of longevityR01AG058762 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Claude Desplan, DANNY REINBERG · 2018 to 2026
$6.2M
NIA NIH HHS R01 AG058762
6 · The paper itself

Abstract

Social insects, such as ants, bees, wasps, and termites, draw biologists' attention due to their distinctive lifestyles. As experimental systems, they provide unique opportunities to study organismal differentiation, division of labor, longevity, and the evolution of development. Ants are particularly attractive because several ant species can be propagated in the laboratory. However, the same lifestyle that makes social insects interesting also hampers the use of molecular genetic techniques. Here, we summarize the efforts of the ant research community to surmount these hurdles and obtain novel mechanistic insight into the biology of social insects. We review current approaches and propose novel ones involving genomics, transcriptomics, chromatin and DNA methylation profiling, RNA interference (RNAi), and genome editing in ants and discuss future experimental strategies.

Indexed as

AnimalsAntsBehavior, AnimalChromatinGenome, InsectGenomicsInsectaRNA InterferenceSingle-Cell AnalysisSocial BehaviorChromatinantsCRISPRepigeneticsRNAisingle-cell sequencingtransgenesis

Identifiers

PMID34116864
PMCPMC8355152
OpenAlexW3172046309

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.