Evidence map›Paper›PMID 34116134›Full record

ArticleMagnetic resonance imaging2021

Feasibility of MR fingerprinting using a high-performance 0.55 T MRI system.

Adrienne E Campbell-Washburn, Yun Jiang, Gregor Körzdörfer, Mathias Nittka, Mark A Griswold

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. 3D Whole-Heart Joint TNMR in biomedicine · 2026
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  9. Cardiac MRI at Low Field Strengths.Journal of magnetic resonance imaging : JMRI · 2024
    Review
  10. Low-field MRI: A report on the 2022 ISMRM workshop.Magnetic resonance in medicine · 2023
    Review
  11. Review
  12. Assessment of MRF for simultaneous TMagma (New York, N.Y.) · 2023
    Article
  13. Low-field MRI: Clinical promise and challenges.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Adrienne E Campbell-WashburnDivision of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States of America. Electronic address: adrienne.campbell@nih.gov.
Yun JiangDepartment of Radiology, Case Western Reserve University, Cleveland, OH, United States of America; Department of Radiology, University of Michigan, Ann Arbor, OH, United States of America. Electronic address: yunjiang@med.umich.edu.
Gregor KörzdörferSiemens Healthcare GmbH, Allee am Roethelheimpark 2, 91052 Erlangen, Germany. Electronic address: gregor.koerzdoerfer@siemens-healthineers.com.
Mathias NittkaSiemens Healthcare GmbH, Allee am Roethelheimpark 2, 91052 Erlangen, Germany. Electronic address: mathias.nittka@siemens-healthineers.com.
Mark A GriswoldDepartment of Radiology, Case Western Reserve University, Cleveland, OH, United States of America. Electronic address: mag46@case.edu.
Case Western Reserve University · USSiemens Healthcare (Germany) · DENational Heart Lung and Blood Institute · US

Funding

Development of high-performance low field MRI technology ZIAHL006257 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2021 to 2025
$8.1M
Intramural NIH HHS ZIA HL006257
6 · The paper itself

Abstract

backgroundMR fingerprinting (MRF) is a versatile method for rapid multi-parametric quantification. The application of MRF for lower MRI field could enable multi-contrast imaging and improve exam efficiency on these systems. The purpose of this work is to demonstrate the feasibility of 3D whole-brain T1 and T2 mapping using MR fingerprinting on a contemporary 0.55 T MRI system. MATERIALS AND

methodsA 3D whole brain stack-of-spirals FISP MRF sequence was implemented for 0.55 T. Quantification was validated using the NIST/ISMRM Quantitative MRI phantom, and T1 and T2 values of white matter, gray matter, and cerebrospinal fluid were measured in 19 healthy subjects. To assess MRF performance in the lower SNR regime of 0.55 T, measurement precision was calculated from 100 simulated pseudo-replicas of in vivo data and within-session measurement repeatability was evaluated.

resultsT1 and T2 values calculated by MRF were strongly correlated to standard measurements in the ISMRM/NIST MRI system phantom (R

conclusionA 3D whole-brain stack-of-spirals FISP MRF sequence is feasible for T1 and T2 mapping at 0.55 T.

Indexed as

BrainMagnetic Resonance ImagingFeasibility StudiesHealthy VolunteersHumansPhantoms, ImagingLow fieldMR fingerprintingQuantitative MRRapid imaging

Identifiers

PMID34116134
PMCPMC8749356
OpenAlexW3170703544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.