Evidence map›Paper›PMID 34116062›Full record

ArticleThe Journal of investigative dermatology2021

Molecular Genetic Dissection of Inflammatory Linear Verrucous Epidermal Naevus Leads to Successful Targeted Therapy.

Melissa Riachi, Satyamaanasa Polubothu, Paulina Stadnik, Connor Hughes, Sara Barberan Martin, Carolyn R Charman, Iek Leng Cheng, Karolina Gholam, Olumide Ogunbiyi, David G Paige and 4 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Melissa RiachiGenetics and Genomic Medicine, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Mosaicism and Precision Medicine Laboratory, The Francis Crick Institute, London, United Kingdom.
Satyamaanasa PolubothuGenetics and Genomic Medicine, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Mosaicism and Precision Medicine Laboratory, The Francis Crick Institute, London, United Kingdom; Paediatric Dermatology, Great Ormond Street Hospital for Children, London, United Kingdom.
Paulina StadnikGenetics and Genomic Medicine, University College London Great Ormond Street Institute of Child Health, London, United Kingdom.
Connor HughesGenetics and Genomic Medicine, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Mosaicism and Precision Medicine Laboratory, The Francis Crick Institute, London, United Kingdom.
Sara Barberan MartinGenetics and Genomic Medicine, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Mosaicism and Precision Medicine Laboratory, The Francis Crick Institute, London, United Kingdom.
Carolyn R CharmanDermatology, Royal Devon and Exeter Hospital, Exeter, United Kingdom.
Iek Leng ChengPharmacy, Great Ormond Street Hospital for Children, London, United Kingdom.
Karolina GholamPaediatric Dermatology, Great Ormond Street Hospital for Children, London, United Kingdom.
Olumide OgunbiyiPaediatric Pathology, Department of Histopathology, Great Ormond Street Hospital for Children, London, United Kingdom.
David G PaigeDermatology, Royal London Hospital, London, United Kingdom.
Neil J SebirePaediatric Pathology, Department of Histopathology, Great Ormond Street Hospital for Children, London, United Kingdom.
Alan PittmanBioinformatics, St George's University of London, London, United Kingdom.
Wei-Li DiImmunobiology Section, Infection, Immunity and Inflammation Programme, University College London Great Ormond Street Institute of Child Health, London, United Kingdom.
Veronica A KinslerGenetics and Genomic Medicine, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Mosaicism and Precision Medicine Laboratory, The Francis Crick Institute, London, United Kingdom; Paediatric Dermatology, Great Ormond Street Hospital for Children, London, United Kingdom. Electronic address: veronica.kinsler@crick.ac.uk.

Funding

Department of Health 17BN22Wellcome TrustWellcome Trust WT104076MA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular BiologyBiopsyCARD Signaling Adaptor ProteinsCase-Control StudiesChildChild, PreschoolConnexin 43FemaleGuanylate CyclaseHumansInfantInflammationKeratinocytesMaleMembrane ProteinsMolecular Targeted TherapyCARD14 protein, humanCARD Signaling Adaptor ProteinsConnexin 43GJA1 protein, humanGuanylate CyclaseMembrane Proteins

Identifiers

PMID34116062
PMCPMC8631607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.