Evidence map›Paper›PMID 34116052›Full record

ArticlePhysiology & behavior2021

Visual food cue processing in children with Prader-Willi Syndrome.

Alexandra P Key, Dorita Jones, Hatun Zengin-Bolatkale, Elizabeth Roof, Hailee Hunt-Hawkins

Open access · greenAbstract read
In one paragraph

Article in Physiology & behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alexandra P KeyVanderbilt Kennedy Center for Research on Human Development; Department of Hearing and Speech Sciences; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center. Electronic address: sasha.key@vumc.org.
Dorita JonesVanderbilt Kennedy Center for Research on Human Development.
Hatun Zengin-BolatkaleDepartment of Hearing and Speech Sciences.
Elizabeth RoofVanderbilt Kennedy Center for Research on Human Development.
Hailee Hunt-HawkinsVanderbilt Kennedy Center for Research on Human Development.
Kennedy Center · DKVanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
NICHD NIH HHS P50 HD103537NICHD NIH HHS U54 HD083211
6 · The paper itself

Abstract

Hyperphagia and the associated interest in food is a characteristic feature of Prader-Willi syndrome (PWS) that emerges during childhood and remains a life-long concern. This study examined neural responses reflecting food cue salience in children with PWS and typical controls, age 3-12 years. Visual event-related potentials were recorded while participants in satiated state passively viewed photographs of high- and low-calorie foods, animals, and neutral objects. Contrary to the prediction, children with PWS did not demonstrate greater than typical neural responses to food, suggesting that it is not an exceptionally motivationally salient stimulus in PWS. Caregiver reports of greater hyperphagia were associated with neural responses to low-calorie foods suggesting accelerated and more fine-grained visual stimulus categorization in terms of edibility and caloric content. Overall, the findings align more closely with the altered satiety rather than increased food reward models of hyperphagia in PWS.

Indexed as

Prader-Willi SyndromeAnimalsChildChild, PreschoolCuesFoodHumansHyperphagiaSatiationEvent-related potentialsFood cues, HyperphagiaPrader-WilliSalienceSatiety

Identifiers

PMID34116052
PMCPMC8287879
OpenAlexW3168345351

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.