Evidence map›Paper›PMID 34115901›Full record

SynthesisAndrologia2021

Absence of SARS-CoV-2 infection in the semen of men recovering from COVID-19 infection: An exploratory study and review of literature.

Aditya Prakash Sharma, Swapnajeet Sahoo, Kapil Goyal, Abhishek Chandna, Sangeetha Kirubanandhan, Vikrant Sharma, Sandeep Grover, Mini P Singh, Ashish Bhalla, Shrawan K Singh

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Andrologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023
    Review
  8. Review
  9. The Impact of the SARS-CoV-2 Pandemic on Reproduction, Sexual Function and Behaviors: A Review of the Main Trends and Findings.International journal of sexual health : official journal of the World Association for Sexual Health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Aditya Prakash SharmaDepartment of Urology, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0003-3071-9916
Swapnajeet SahooDepartment of Psychiatry, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0003-0365-7086
Kapil GoyalDepartment of Virology, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0002-5864-6221
Abhishek ChandnaDepartment of Urology, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0002-9398-2167
Sangeetha KirubanandhanDepartment of Virology, PGIMER, Chandigarh, India.
Vikrant SharmaRegional VDRL, Department of virology, PGIMER, Chandigarh, India.
Sandeep GroverDepartment of Psychiatry, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0002-2714-2055
Mini P SinghDepartment of Virology, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0001-6263-1850
Ashish BhallaDepartment of Internal Medicine, PGIMER, Chandigarh, India.ORCID https://orcid.org/0000-0001-5210-1012
Shrawan K SinghDepartment of Urology, PGIMER, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of COVID-19 on the male reproductive tract has been sparsely studied. This exploratory study was designed to determine the presence of SARS-CoV-2 in the semen of men recovering from COVID-19. A systematic literature review was also performed as per PRISMA guidelines to gather perspective on this topic. The prospective study included men 21 years and older recovering from COVID-19 with nasopharyngeal swab negative for SARS-CoV-2 or at least two weeks from the last COVID RT-PCR positivity. After clinical evaluation, freshly ejaculated semen sample by masturbation was collected in a sterile container. Samples were processed for the detection of SARS-CoV-2 by RT-PCR. Twenty-one patients were contacted for the study, 11 of which consented to provide a semen sample. The mean age of the cohort was 29.72 ± 4.52 years. None of the patients gave a history of epididymo-orchitis or sexual dysfunction at the time of assessment. None of the semen samples demonstrated SARS-CoV-2 on RT-PCR. Median duration of semen sample collection from the COVID positivity was 44 days (Range 19-59 days). Detailed literature review revealed that SARS-CoV-2 is not found in patients recovering from COVID-19 infection. We conclude that SARS-CoV-2 is not found in the semen of patients recovering from COVID-19.

Indexed as

COVID-19SARS-CoV-2AdultHumansMaleProspective StudiesRNA, ViralSemenRNA, Viralcarrier stateCOVID-19SARS-CoV-2semenvirus

Identifiers

PMID34115901
PMCPMC8420368
OpenAlexW3171475441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.