ArticlePloS one2021
Experiences with implementation of continuous positive airway pressure for neonates and infants in low-resource settings: A scoping review.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Continuous positive airway pressure versus methylxanthine for apnoea in preterm infants.The Cochrane database of systematic reviews · 2025Pooled it
- The Care of Preterm and Term Newborns with Respiratory Conditions: A Systematic Synthesis of Evidence from Low- and Middle-Income Countries.Neonatology · 2025Pooled it
- Guideline
- Article
- Feasibility of integration of a novel bCPAP system into the NICU of a Public Referral Hospital in Mysuru, India.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Patient and caregiver perceptions of oxygen therapy in facility-based settings for acute hypoxemic conditions: a scoping review.Journal of global health · 2025Article
- Article
- Article
- Evaluating the Feasibility of a Nonelectric Bubble CPAP System in the NICU of a Philippine Regional Referral Hospital: A Qualitative Study.International journal of pediatrics · 2025Article
- A survey on the use of continuous positive airway pressure in newborn care in Kenya in 2017-2018.PloS one · 2025Article
- Implementation of a novel bubble continuous positive airway pressure system with a blender in preterm infants in a low resource setting.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Management of neonates with respiratory distress syndrome in resource-limited settings.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Oral appliance therapy and hypoglossal nerve stimulation as non-positive airway pressure treatment alternatives for obstructive sleep apnea: a narrative expert review.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Vayu bubble continuous positive airway pressure is a promising solution with favorable treatment outcomes for respiratory distress syndrome in newborns: a qualitative study in Bangladesh.Frontiers in pediatrics · 2024Article
- Inter-rater reliability of the Silverman and Andersen index-a measure of respiratory distress in preterm infants.PloS one · 2023Article
- Feasibility and usability of a very low-cost bubble continuous positive airway pressure device including oxygen blenders in a Ugandan level two newborn unit.PLOS global public health · 2023Article
- Incidence of nasal pressure injury in preterm infants on nasal mask noninvasive ventilation.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023Observational
- Effectiveness of a novel bubble CPAP system for neonatal respiratory support at a referral hospital in the Philippines.Frontiers in pediatrics · 2023Article
- Article
- Respiratory distress syndrome management in resource limited settings-Current evidence and opportunities in 2022.Frontiers in pediatrics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContinuous positive airway pressure (CPAP) is the gold standard of care in providing non-invasive positive pressure support to neonates in respiratory distress in high-resource settings. While safety has been demonstrated in low-resource settings, there is a lack of knowledge on the barriers and facilitators to proper implementation.
objectiveTo identify and describe the barriers, facilitators, and priorities for future implementation of CPAP for neonates and infants in low-resource settings.
methodsA systematic search (database inception to March 6, 2020) was performed on MEDLINE, Embase, Web of Science, CINAHL, Global Health, and the WHO Global Index Medicus using PRISMA-ScR guidelines. Original research articles pertaining to implementation of CPAP devices in low-resource settings, provider or parent perspectives and experiences with CPAP, cost-benefit analyses, and cost-effectiveness studies were included. Inductive content analysis was conducted.
findings1385 article were screened and 54 studies across 19 countries met inclusion criteria. Six major themes emerged: device attributes, patient experiences, parent experiences, provider experiences, barriers, and facilitators. Nasal trauma was the most commonly reported complication. Barriers included unreliable electricity and lack of bioengineering support. Facilitators included training, mentorship and empowerment of healthcare providers. Device design, supply chain infrastructure, and training models were imperative to the adoption and sustainability of CPAP.
conclusionSustainable implementation of CPAP in low resource settings requires easy-to-use devices, ready access to consumables, and holistic, user-driven training. Further research is necessary on standardizing metrics, interventions that support optimal provider performance, and conditions needed for successful long-term health system integration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.