Evidence map›Paper›PMID 34115767›Full record

ArticlePloS one2021

In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~.

Kensuke Takagi, Akihito Tanaka, Naoki Yoshioka, Yasuhiro Morita, Ruka Yoshida, Yasunori Kanzaki, Naoki Watanabe, Ryota Yamauchi, Shotaro Komeyama, Hiroki Sugiyama and 8 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Kensuke TakagiDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.ORCID 0000-0003-3999-8536
Akihito TanakaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Naoki YoshiokaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Yasuhiro MoritaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Ruka YoshidaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yasunori KanzakiDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Naoki WatanabeDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Ryota YamauchiDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Shotaro KomeyamaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Hiroki SugiyamaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Kazuki ShimojoDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Takuro ImaokaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Gaku SakamotoDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Takuma OhiDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Hiroki GotoDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Hideki IshiiDepartment of Cardiology, Fujita Health University Bantane Hospital, Nagoya, Japan.ORCID 0000-0003-4348-0123
Itsuro MorishimaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Toyoaki MuroharaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ogaki Municipal Hospital · JPNagoya University · JPFujita Health University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo clarify the association of detailed angiographic findings with in-hospital outcome after primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction (STEMI) in Japan.

backgroundData regarding the association of detailed angiographic findings with in-hospital outcome after STEMI are limited in the p-PCI era.

methodsBetween January-2004 and December-2018, 1735 patients with STEMI (mean age, 68.5 years; female, 24.6%) who presented to the hospital in the 24-hours after symptom onset and underwent p-PCI were evaluated using the disease registries. The registry is an ongoing, retrospective, single-center hospital-based registry.

resultsThe 30-day mortality rate and in-hospital mortality rate were 7.7% and 9.2%, respectively. Independent predictors of in-hospital mortality were ejection fraction (EF) < 40% [adjusted Odds Ratio (aOR), 4.446, p < 0.001], culprit lesions in the left coronary artery (LCA) (aOR, 2.940, p < 0.001) compared with those in the right coronary artery, Killip class > II (aOR, 7.438; p < 0.001), chronic kidney disease (CKD) (aOR, 4.056; p < 0.001), final thrombolysis in myocardial infarction (TIMI) grades 0/1/2 (aOR, 1.809; p = 0.03), absence of robust collaterals (aOR, 17.309; p = 0.01) and hypertension (aOR, 0.449; p = 0.01).

conclusionsAmong the consecutive patients with STEMI, the in-hospital mortality rate after p-PCI significantly improved in the second half. Not only CKD, Killip class > II, and EF < 40%, but also the angiographic findings such as culprit lesions in the LCA, absence of very robust collaterals, and final TIMI grades <3 were associated with an increased risk of in-hospital mortality.

Indexed as

AgedFemaleHospital MortalityHospitalsHumansMaleMiddle AgedOdds RatioPercutaneous Coronary InterventionRetrospective StudiesRisk AssessmentRisk FactorsST Elevation Myocardial Infarction

Identifiers

PMID34115767
PMCPMC8195354
OpenAlexW3167591796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.