Evidence map›Paper›PMID 34115340›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2021

"I want to feel young again": experiences and perspectives of young people who inject drugs living with hepatitis C in Vancouver, Canada.

Jessica Jacob, Trevor Goodyear, Pierre-Julien Coulaud, Peter Hoong, Lianping Ti, Rod Knight

Abstract read
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica JacobBritish Columbia Centre on Substance Use, 400-1045 Howe St, Vancouver, V6Z 2A9, BC, Canada.
Trevor GoodyearBritish Columbia Centre on Substance Use, 400-1045 Howe St, Vancouver, V6Z 2A9, BC, Canada.
Pierre-Julien CoulaudBritish Columbia Centre on Substance Use, 400-1045 Howe St, Vancouver, V6Z 2A9, BC, Canada.
Peter HoongBritish Columbia Centre on Substance Use, 400-1045 Howe St, Vancouver, V6Z 2A9, BC, Canada.
Lianping TiBritish Columbia Centre on Substance Use, 400-1045 Howe St, Vancouver, V6Z 2A9, BC, Canada.
Rod KnightBritish Columbia Centre on Substance Use, 400-1045 Howe St, Vancouver, V6Z 2A9, BC, Canada. bccsu-rk@bccsu.ubc.ca.ORCID http://orcid.org/0000-0002-1464-1584

Funding

Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
CIHR PJT - 148922NIDA NIH HHS R25 DA037756
6 · The paper itself

Abstract

objectivesPeople who inject drugs (PWID) are disproportionately impacted by hepatitis C virus (HCV). Despite the availability and efficacy of direct-acting antiviral (DAA) HCV therapies, treatment rates remain low among PWID. Among PWID, those who are young (under age 30) experience high rates of HCV and also face distinct barriers to care. The objective of this study is to identify facilitators and barriers to navigating various facets of the HCV cascade of care, including DAA treatment access, among young PWID.

methodsWe draw on data from in-depth, semi-structured interviews conducted between May and November 2019 with a sample of 11 young, street-involved PWID who have lived experience of HCV and who live in Metro Vancouver, Canada. Informed by a social constructivist epistemology, data were thematically analyzed using an equity-oriented theoretical framework.

resultsOur analysis yielded two key themes. First, participants described facilitators to HCV care access, including individual factors (e.g., desire to be cured, knowledge of side effects) and healthcare and socio-contextual factors (e.g., peer supports, supportive youth-specific services). Second, participants described a contrasting set of barriers to HCV care access, including concerns over treatment side effects and (in)eligibility, complex healthcare system navigation, substance use- and housing-related stigma, and clinician gatekeeping of DAAs.

conclusionFindings from this study underscore the need for HCV-related knowledge-building efforts among young PWID and clinicians. Also needed are structural policy interventions to facilitate access to DAAs, including anti-stigma efforts, access to safe housing, and the scale-up of low-barrier youth-specific services and decentralized HCV care.

Indexed as

Health Knowledge, Attitudes, PracticeHepatitis CSubstance Abuse, IntravenousAntiviral AgentsCanadaHealth Services AccessibilityHumansQualitative ResearchYoung AdultAntiviral AgentsDirect-acting antiviralsHepatitis CPeople who inject drugsQualitative researchTreatmentYouth

Identifiers

PMID34115340
PMCPMC8523650

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.