Evidence map›Paper›PMID 34115260›Full record

ArticleInternational urology and nephrology2022

Acid base disorders in patients with COVID-19.

Gaetano Alfano, Francesco Fontana, Giacomo Mori, Francesco Giaroni, Annachiara Ferrari, Silvia Giovanella, Giulia Ligabue, Elisabetta Ascione, Silvia Cazzato, Marco Ballestri and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

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  9. COVID-19-Induced Diabetes Mellitus: Comprehensive Cellular and Molecular Mechanistic Insights.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  10. Review
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  12. [Acid-base balance and long COVID: comments on metabolic-respiratory alterations].Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 1 institution in 1 country.

Gaetano AlfanoSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy. gaetano.alfano@unimore.it.ORCID https://orcid.org/0000-0003-0591-8622
Francesco FontanaNephrology Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Giacomo MoriNephrology Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Francesco GiaroniSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Annachiara FerrariSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Silvia GiovanellaSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Giulia LigabueSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Elisabetta AscioneNephrology Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Silvia CazzatoSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Marco BallestriNephrology Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Margherita Di GaetanoClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Marianna MeschiariClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Marianna MenozziClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Jovana MilicPhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Bedini AndreaClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Erica FranceschiniClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Gianluca CuomoClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Riccardo MagistroniSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Cristina MussiniClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Gianni CappelliSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University Hospital of Modena and Reggio Emilia, via del Pozzo, 71, 41124, Modena, Italy.
Giovanni GuaraldiClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Modena Covid-19 Working Group (MoCo19)
University of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcid-base derangement has been poorly described in patients with coronavirus disease 2019 (COVID-19). Considering the high prevalence of pneumonia and kidneys injury in COVID-19, frequent acid-base alterations are expected in patients admitted with SARS-Cov-2 infection. The study aimed to assess the prevalence of acid-base disorders in symptomatic patients with a diagnosis of COVID-19.

methodsThe retrospective study enrolled COVID-19 patients hospitalized at the University Hospital of Modena from 4 March to 20 June 2020. Baseline arterial blood gas (ABG) analysis was collected in 211 patients. In subjects with multiple ABG analysis, we selected only the first measurement. A pH of less than 7.37 was categorized as acidemia and a pH of more than 7.43 was categorized as alkalemia.

resultsABG analyses revealed a low arterial partial pressure of oxygen (PO

conclusionVariations of pH occurred in the majority (79.7%) of patients admitted with COVID-19. The patients experienced all the type of acid-base disorders, notably metabolic and respiratory alkalosis were the most common alterations in this group of patients.

Indexed as

Acid-Base ImbalanceAgedAged, 80 and overBlood Gas AnalysisCOVID-19FemaleHospitalizationHumansItalyMaleMiddle AgedRetrospective StudiesRisk FactorsSurvival RateAcid–base equilibriumAcid lacticAlkalosisKidney diseaseMetabolic acidosisSARS-CoV-2

Identifiers

PMID34115260
PMCPMC8193956
OpenAlexW3166572870

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.