Evidence map›Paper›PMID 34114809›Full record

ArticleJournal of the American Chemical Society2021

Multiplex and In Vivo Optical Imaging of Discrete Luminescent Lanthanide Complexes Enabled by In Situ Cherenkov Radiation Mediated Energy Transfer.

Kirsten E Martin, Alexia G Cosby, Eszter Boros

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Single Molecule EuJournal of the American Chemical Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025
    Review
  6. Review
  7. Targeted, Molecular EuropiumJournal of the American Chemical Society · 2023
    Article
  8. ReversibleRSC advances · 2023
    Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kirsten E MartinDepartment of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, New York 11794, United States.
Alexia G CosbyDepartment of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, New York 11794, United States.ORCID 0000-0002-2222-3497
Eszter BorosDepartment of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, New York 11794, United States.ORCID 0000-0002-4186-6586

Funding

Chemical Biology Training InterfaceT32GM136572 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELIZABETH M BOON, Jessica Chuang Seeliger · 2020 to 2026
$2.9M
SBU Chemistry-Biology Interface Training ProgramT32GM092714 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S, TONGE, PETER J · 2010 to 2019
$1.7M
Cherenkov luminescence mediated excitation of discrete lanthanide optical probesR21EB030071 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI BOROS, ESZTER · 2021 to 2024
$610k
NIBIB NIH HHS R21 EB030071NIGMS NIH HHS T32 GM092714NIGMS NIH HHS T32 GM136572
6 · The paper itself

Abstract

Recently, we pioneered the application of Cherenkov radiation (CR) of radionuclides for the in situ excitation of discrete Eu(III) and Tb(III) complexes. CR is produced by isotopes decaying under emission of charged particles in dielectric media and exhibits a maximum intensity below 400 nm. We have demonstrated that luminescent lanthanide antenna complexes are ideal acceptors for Cherenkov radiation-mediated energy transfer (CRET). Here, we develop and assess peptide-functionalized Tb(III) and Eu(III) complexes in conjunction with CRET excitation by the positron emissive radioisotope

Indexed as

Optical ImagingAnimalsCell Line, TumorCoordination ComplexesEnergy TransferLanthanoid Series ElementsLigandsMaleMiceMice, NudeMolecular ConformationNeoplasms, ExperimentalPeptidesCoordination ComplexesLanthanoid Series ElementsLigandsPeptides

Identifiers

PMID34114809
PMCPMC9694337

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.