ArticleCancer reports (Hoboken, N.J.)2022
Outcome of childhood acute lymphoblastic leukemia treatment in a single center in Brazil: A survival analysis study.
Article in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Epidemiological Profile of Pediatric Patients with Acute Lymphoblastic Leukemia Admitted to Four Hospitals in Curitiba, Southern Brazil.Medical sciences (Basel, Switzerland) · 2026Article
- Hospitalization in the Intensive Care Unit of Children with Acute Lymphoblastic Leukemia: A Retrospective Cohort Study.Medical journal of the Islamic Republic of Iran · 2026Article
- Acute lymphoblastic leukemia: an update on treatment and Brazilian perspective.Frontiers in oncology · 2026Review
- Relapse risk and outcome of discontinuing asparaginase in children with acute lymphoblastic leukemia.Annals of hematology · 2025Article
- Insights into Asparaginase Allergic Responses: Exploring Pharmacogenetic Influences.Pharmaceutics · 2024Review
- The survival of childhood leukemia: An 8-year single-center experience.Cancer reports (Hoboken, N.J.) · 2023Article
- Association of the clinical profile and overall survival of pediatric patients with acute lymphoblastic leukemia.Frontiers in pediatrics · 2023Article
- Retrospective analysis of outcomes for pediatric acute lymphoblastic leukemia in South American centers.Frontiers in oncology · 2023Article
- Outcome of childhood acute lymphoblastic leukemia treatment in a single center in Brazil: A survival analysis study.Cancer reports (Hoboken, N.J.) · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute lymphoblastic leukemia (ALL) is the most common neoplasm in childhood. The probability of current overall survival (OS) is around 90% in developed countries. There are few studies that demonstrate the results in Brazil.
aimThis work aims to analyze the results of children with ALL treated at a single institution in Rio de Janeiro. METHODS AND
resultsRetrospective analysis survival study of a cohort of childhood ALL patients treated in Hemorio. Kaplan-Meier and log-rank methods were used for the analysis of OS and events-free survival (EFS) and the Cox proportional hazards regression model for multivariate analysis. The probability of OS and EFS at 6 years was 52% and 45%. The probability of OS and EFS in 6 years for patients aged 10-17 years was 31% and 28% and for the younger was 65% and 55%, respectively (p < .001). A probability of OS and EFS in 6 years for patients with more than 100 000 leukocytes/mm
conclusionsThe presence of a high number of adolescents and high-risk patients, as well as many patients who discontinued the use of asparaginase or any substitute led to a lower probability of OS and EFS in our cohort.
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